Pd(PPh_3)_4催化Suzuki偶联反应合成4-溴-2-氟-联苯
Pd(PPh3)4 作为一种重要催化剂[1],常用于催化偶联反应(Cross- Coupling Reaction)的进行,是构建碳-碳键的一种重要方法,其特点是催化条件温和。例如,在Pd(PPh3)4和Ag2O 的共同作用下,苯硼酸与芳香卤代烃直接反应生成联苯类化合物,该反应的产率达到了90% (式1)[2,...
Zhou, Wen-Jun,Wang, Ke-Hu,Wang, Jin-Xian.Pd(PPh 3 ) 4 -PEG 400 catalyzed protocol for the atom-efficient stille cross-coupling reaction of organotin with aryl bromides.Journal of Organic Chemistry. 2009Pd (PPh3)4-PEG 400 catalyzed protocol for the atom-efficient Stille cross-coupling ...
关键词:Suzuki偶联反应;4一溴_2一氟一联苯;催化;精细化工中间体 中图分类号:0625.2 文献标识码:A 文章编号:1003—5214(2012)11—1142—03 Synthesisof4-Bromo-2-nu0r0biphenylbySuzukiCoupling ReactionwithPd(PPh3)4Catalysis GAOFeng.qin,HEHan-jiang ,WANGXiao—ming,GUOQiang (1.XianyangNormalUniversity,Xianya...
Does any one have a trick to removing Pd(PPh3)4from a cross-coupling reaction? In my case I did a Negishi coupling. VinylMgCl was cooled to 0C and THF soln of ZnBr2 is added and stirred for 15 min. My vinyl iodide was dissolved in THF and 0.03 eq Pd(PPh3)4 was added. The hom...
相比较其实氯亚钯酸钾也蛮贵的。还是买划算，催化的话用量很少的，买1克就够得你用了。
氨基脱烯丙基Pd(pph3)4 NDMBA 下载积分:100 内容提示: J. Org. Chem. 1993,58, 6109-6113 6109 Notes Mild and Selective Palladium(0)-Catalyzed Deallylation of Allylic Amines. Allylamine and Diallylamine as Very Convenient Ammonia Equivalents for the Synthesis of Primary Amines Florence Garro-Helion...
Pd(PPh3)4 CAS:14221-01-3 英文名称:Tetrakis(triphenylphosphine) palladium(0) 产品含量:98%,外观:金黄色结晶粉末/99%,Pd>9.2%,包装: 14221-01-3;四(三苯基膦)钯, Pd(PPh3)4可定制,可提供COA、MSDS、产品检测方法,工艺流程等各类文件。 武汉欣扬瑞和化学科技有限公司始建于2001年,总投资8000余万元。主...
(theTsuji-Trostreaction)hasincreasedtheuseof allylicgroupsinprotectivegroupchemistrybyofferinga newgeneralmethodfordeprotection.Oftheallylic protectinggroups,theallylgroup(All)andtheallyloxy- carbonylgroup(Alloc)arethemostcommonlyemployed, theformerfortheprotection,interalia,ofcarboxylicacids, phosphoricacids,or...
目前,商品化的Pd(PPh3)4, Pd(OAc)2和Pd2(dba)3都是常用的催化剂。但是,这种传统的均相Pd基催化剂存在多种弊端,例如Pd的价格昂贵,而且用作配体的大部分膦化合物都有剧毒,反应条件要求苛刻,对空气不稳定等。并且,这种均相的催化体系不能回收重复利用。极大地限制了这些均相催化剂在工业上的应用。所以探索新的无...