charged with 130 mL of CH2Cl2, the alcohol prepared in Step A (10.4 g, 40.0 mmol), and ...
与MnO2 比较,氧化能力较强,制备方便。PDC 的氧化能力和反应溶剂有关,PDC用DMF当溶剂可以将伯醇氧化为酸,而在 CH2Cl2 中则将伯醇、仲醇、苄醇和烯丙基醇稳定地转变为相应的醛酮化合物。通过选用不同的溶剂,PDC 许多时候可以取代 PCC 和 MnO2 在有机合成中的许多功能。另外PDC还可将环状半缩醛氧化成为相应的内...
A 500-mL, round-bottomed flask equipped with a 4.5-cm, egg-shaped Teflon-coated magnetic stir bar ischarged with 130 mL of CH2Cl2, the alcohol prepared in Step A (10.4 g, 40.0 mmol), and 15 g of freshly powdered 3 Å molecularsieves. Pyridinium chlorochromate (21.5 g, 100mmol) is ...
Oxidation of Primary Alcohols to Aldehydes using PCC Description:Treatment of alcohols with PCC leads to formation of the aldehyde. Real-Time Example: Org. Synth. 1967, 47, 25 DOI Link: 10.15227/orgsyn.047.0025 Click to Flip Comments