ca. 0.2–1.2 g of activated MS per mmol of alcohol areadded in order to accelerate the reaction. In order to moderate the acidity ofPCC, it is very common to add
ca. 0.2–1.2 g of activated MS per mmol of alcohol areadded in order to accelerate the reaction. In order to moderate the acidity ofPCC, it is very common to add
When a TLC analysis shows that most ofthe starting alcohol is consumed, the solids suspended in the reaction andthe chromium species are removed by filtration through a pad of Florisil1,silica gel, alumina or Celite, and the pad is washed with an organic solvent,such as ether, DCM, or EtO...
charged with 130 mL of CH2Cl2, the alcohol prepared in Step A (10.4 g, 40.0 mmol), and ...
When a TLC analysis shows that most ofthe starting alcohol is consumed,the solids suspended in the reaction andthe chromium species are removed by filtration through a pad of Florisil1,silica gel, alumina or Celite, and the pad is washed with an or...
When a TLC analysis shows that most ofthe starting alcohol is consumed,the solids suspended in the reaction andthe chromium species are removed by filtration through a pad of Florisil1,silica gel, alumina or Celite, and the pad is washed with an organic solvent,such as ether, DCM, or EtOAc...
One key aspect to consider when performing PCC oxidation is the potential for side reactions, such as over-oxidation of the alcohol to form carboxylic acids. To minimize these side reactions, it is essential to carefully control the reaction conditions, such as temperature and reaction time. Addit...
In this reaction of the alkene, the correct answer is below but I don't understand why it goes to that. This is my thought process - reagents 1 and 2 do oxymercuration demercuration and makes a secondary alcohol, then reagent 3 turns the alcohol into a ketone, and finally reagent 4 an...
When a TLC analysis shows that most ofthe starting alcohol is consumed,the solids suspended in the reaction andthe chromium species are removed by filtration through a pad of Florisil1,silica gel, alumina or Celite, and the pad is washed with an organic solvent,such as ether, DCM, or EtOAc...
popularization and application. In the process of synthesizing lactone natural products, we need to oxidize lactone alcohol to lactone aldehyde, but the lactone ring is easily destroyed under strong conditions, so PCC is selected to carry out this kind of oxidation reaction under suitable conditions....