六个供体的PBMC分别经尾静脉注射入六组M-NSG小鼠体内,可检测到人源CD45+细胞比例总体趋势升高,其嵌合比例变化有差异,总体变化趋势符合预期。小鼠体重变化相对稳定。 药效评价 图2.Hu-PBMCH929骨髓瘤细胞荷瘤小鼠模型的抗肿瘤药效 图3.Hu-PBMCA431表皮癌细胞荷瘤小鼠模型的抗肿瘤药效 ...
六个供体的PBMC分别经尾静脉注射入六组M-NSG小鼠体内,可检测到人源CD45+细胞比例总体趋势升高,其嵌合比例变化有差异,总体变化趋势符合预期。小鼠体重变化相对稳定。 药效评价 图2.Hu-PBMCH929骨髓瘤细胞荷瘤小鼠模型的抗肿瘤药效 图3.Hu-PBMCA431表皮癌细胞荷瘤小鼠模型的抗肿瘤药效 ...
Cíntia M.F. RezendeTércio S GoesVinícius S GoesVasco AzevedoAlfredo M GoesElsevier B.V.Immunology LettersRezende CM, Goes TS, Goes VS, et al. GM-CSF and TNF-alpha syn- ergize to increase in vitro granuloma size of PBMC from humans in- duced by Schistosoma mansoni recombinant 28-kDa ...
一种PBMC体外培养基及其制备方法[发明专利](19)中华人民共和国国家知识产权局 (12)发明专利申请 (10)申请公布号 (43)申请公布日 (21)申请号 202010227836.0 (22)申请日 2020.03.27 (71)申请人 郑州鲲鹏健康科技有限公司 地址 450000 河南省郑州市市辖区高新技 术产业开发区长春路河南省国家大学 科技园y17-3...
Laspiur JP, Anderson ER, Ciborowski P, Wojna V, Rozek W, Duan F, Mayo R, Rodriguez E, Plaud-Valentin M, Rodriguez-Orengo J, Gendelman HE, Melendez LM: CSF proteomic fingerprints for HIV-associated cognitive impairment. J Neuroimmunol 2007, 192: 157–170. 10.1016/j.jneuroim.2007.08.004...
Cell populations from hPBMC and GM-CSF secretion induced by immunostimulatory ODNs.Juan M. RodríguezJosé MarchicioMariela LópezAndrea ZiblatFernanda EliasJuan FlóRicardo A. LópezDavid HornJorge ZorzopulosAlejandro D. Montaner
Levels of HIV DNA in PBMC and CSF cell pellets.Michelli, Faria de OliveiraSara, GianellaScott, LetendreKonrad, SchefflerSergei, L. Kosakovsky PondDavey, M. SmithMatt, StrainRonald, J. Ellis
Median production of canonical NK cytokines, IFN-y and GM-CSF, at day 14 was over 5-fold greater in PBMC-expanded (IFN-y=316.7pg/mL, GM-CSF=267.0pg/mL) compared to CD5-depleted NK cells (IFN-y=59.6pg/mL, GM-CSF=48.7pg/mL) (P=NS). Sequencing data showed principal component ...
The NSG-SGM3 mouse expresses human KITLG, CSF2 and IL-3 as transgenes and supports increased development of human myeloid and Treg populations following engraftment with umbilical cord CD34+ hematopoietic stem cells as compared to NSG mice. We hypothesized that PBMC-engraftment of NSG-SGM3 mice ...
Effect of PDC cell depletion from hPBMC on GM-CSF secretion induced by immunostimulatory ODNs.Juan M. RodríguezJosé MarchicioMariela LópezAndrea ZiblatFernanda EliasJuan FlóRicardo A. LópezDavid HornJorge ZorzopulosAlejandro D. Montaner