Objectives: To determine if lorazepam or zopiclone is more effective in providing a restful night of sleep and to assess the effects of these medications on cognition. Design: A randomized, double-blinded, crossover trial was performed at a tertiary care rehabilitation inpatient unit in a teaching...
The article investigates the cost-effectiveness of the most commonly used sedatives prescribed for mechanically ventilated critically ill patients. Base-case probabilistic analysis shows that propofol dominated lorazepam in 91% of simulations and, on average, was both $6,378 less expensive per patient ...
Role of the Funder/Sponsor: The funding source had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and the decision to submit the manuscript for publication. Meeting Presentation...
When benzodiazepines are considered, shorter half-life agents (eg, etizolam, oxazepam, or lorazepam) are preferred. Further, extrapyramidal symptoms should be avoided/treated owing to the risk of swallowing difficulties that can increase pneumonia risk. Pharmacokinetic and pharmacodynamic drug-drug ...
Progress in Neuro-Psychopharmacology & Biological Psychiatry: An International Research, Review and News JournalHuang TL, Hung YY (2009) Lorazepam reduces the serum brain- derived neurotrophic factor level in schizophrenia patients with catatonia. Progress in Neuropsychopharmacol and Biological Psychiatry 33...
This review of diagnosis and management of acute bacterial and viral infections in the CNS provides a general approach to patients with a suspected CNS infection and also provides a more detailed review of the diagnosis and management of patients with suspected bacterial meningitis, viral encephalitis...
lora- zepam was reported to be useful in cases of AIDS-associated psychosis with catatonia.28 However, in a systematic review, patients with AIDS treated with lorazepam developed confusion and were oversedated, resulting in discontinuation of the drug.26 Older...
Generalized estimating equations analysis was used to independently evaluate association within patients over successive days of intensive care and yielded a similar result (odds ratio, 2.3; P< .001). Richmond Agitation-Sedation Scale (RASS) Scores vs Cumulative Lorazepam Equivalent Dose Benzodiazepine ...
Pathophysiology of septic encephalopathy: a review. Crit Care Med.2000;28:3019-3024.http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&Dopt=r&uid=entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10966289&dopt=AbstractGoogle Scholar 13. Bleck TP, Smith MC, Pierre-...
of interventions for psychiatric conditions commonly prevalent among end-stage cancer patients; the review study assessed the state of the research into treatment effectiveness. Furthermore, the review study attempted to include non-traditional (i.e., alternative) therapies that have undergone scientific...