The respiratory system and cardiovascular work closely together to make sure that organ tissues obtain sufficient oxygen. Oxygen is vital for cellular functions. The air inhaled in and kept in the lungs is transported to the blood. The blood is circulated by the heart, which pumps the oxygenated...
After utilization for protein synthesis, over 90% of dietary tryptophan is converted to KYN by one of two rate-limiting enzymes: by TDO in the liver under healthy conditions and by IDO in various human tissues (e.g., intestines, lungs, placenta, kidneys, spleen, blood and brain) under inf...
there are two types of cell polarity: apicobasal polarity (AP) and planar cell polarity (PCP). While AP divides the plasma membrane into the apical domain and basal
In vivo, our experiments demonstrate that CO at a low concentration protects the lungs, extends the survival of the animals, and exerts potent anti-inflammatory effects with reduced inflammatory cell influx into the lungs and marked attenuation in the expression of pro-inflammatory cytokines....
A variety of cardiac conditions, including sudden infant death syndrome, alongside common adult diseases like hypertension, myocardial ischemia, cardiac arrhythmias, myocardial infarction, and heart failure, suggest a role for a modified sympathetic nervous system. Despite numerous investigations into the di...
When cells undergo oxidative stress, the oxidation or adduct formation of the cysteine residues of KEAP1 by ROS or electrophiles takes place which leads to the conformational changes of KEAP1. Although KEAP1 still binds to the DLG and ETGE motifs of Nrf2 by its kelch domain, it fails to ...
Trace the blood flow from an air sac in the lungs through the right kidneys to the right atrium of the heart. Trace the flow of blood from the heart to the kidney and then back to the heart. Trace the flow of blood from the vena cava to the aorta listing eac...
3. Trace blood flow through the systemic circuit to the heart, through the heart to the pul Trace the blood flow from an air sac in the lungs through the right kidneys to the right atrium of the heart. Explain the pathway of blood flow through the...
The lungs of the normal mice and tumor-bearing mice were examined by HE staining. MD simulations The system was neutralized with the counter ions of Na+. The whole system was immersed in a rectangular box of TIP3P water molecules, and the water box was extended 12 Å from any solute...
PFUs (2 × 105) of the tissue culture-grown Smith strain of MCMV (VR-194; ATCC, Manassas, VA) were injected into the footpads of the different mouse strains. Three weeks after infection, salivary glands and lungs were collected under sterile conditions and stored at -70°C. The virus ti...