Capen CC. Pathophysiology of chemical injury of the thyroid gland. Toxicol Lett.1992;64 - 65(Spec No.):381-388.Capen,C. C.Pathophysiology of chemical injury of the thyroid gland.Toxicology Letters. 1992C. C. Capen.Pathophysiology of chemical injury of the thyroid gland. Toxicology Letters ...
Many goitrogenic xenobiotics that increase the incidence of thyroid tumors in rodents exert a direct effect on the thyroid gland to disrupt one of several possible steps in the biosynthesis and secretion of thyroid hormones. This includes: (1) inhibition of the iodine trapping mechanism (thiocyanate...
This is probably due to an increase in the number of pituitary gonadotropin-releasing hormone (GnRH) receptors, but there is probably no change in GnRH input to the pituitary gland [14]. At this time, the amplitude of the LH pulses increases drastically even if the frequency of LH pulses ...
The gland is made of two embryologically and functionally distinct units: the cortex (outer layer and endocrine) and medulla (inner layer and neurocrine). The cortex is derived from the intermediate mesoderm of the urogenital ridge in the fifth week of gestation as mesenchymal cells proliferate to...
Hypothyroidism is a condition in which the production and secretion of thyroid hormones from the thyroid gland are reduced, resulting in a compensatory elevation of TSH hormone. TSH is a pituitary gland hormone whose circulating level is independently associated with the prevalence of carotid plaques ...
Hypothyroidism is a condition in which the production and secretion of thyroid hormones from the thyroid gland are reduced, resulting in a compensatory elevation of TSH hormone. TSH is a pituitary gland hormone whose circulating level is independently associated with the prevalence of carotid plaques ...
The process of goitrogenesis is likely to be the consequence of an increased TSH stimulation linked to an initial reduction of circulating thyroid hormone caused by iodine deficiency (ID). Other growth factors associated to TSH may have a role in the pathogenesis of goiter. Natural history of ...
Cell-based imaging of sodium iodide symporter activity with the yellow fluorescent protein variant YFP-H148Q/I152L. The sodium iodide symporter (NIS) mediates iodide (I(-)) transport in the thyroid gland and other tissues and is of increasing importance as a therapeutic ... KJ Rhoden,S Cian...
of similarity between immunogenic epitopes of SARS-CoV-2 and various human self-tissue proteins, such as adipose tissue, blood, eye, brain, pituitary gland, thyroid gland, gastrointestinal tract, heart muscle, kidney, liver, lung, skeletal muscle, skin, testes, and many other proteins [47]. ...
The broad category of thyroiditis includes the following inflammatory diseases of the thyroid gland: (1) acute suppurative thyroiditis, which is due to bacterial infection; (2) subacute thyroiditis, which results from a viral infection of the gland; and (3) chronic thyroiditis (also known as Hash...