FractureIntramedullarynailingReamerFatembolismPrimary operative stabilization by an intramedullary procedure is the treatment of first choice for fractures of long tubular bones for reasons of biomechanics, the minimally invasive approach, and the early loadability of the injured limb. Additionally, in the ...
His 1872 publication documented nerve injury and subsequent contracture from compartment syndrome following supracondylar fracture. [8] That injury remains known as Volkmann contracture. Although long bone fractures are a common cause of compartment syndrome, other injuries are also a common antecedent ...
Fracture during adulthood (age ≥ 50 years) Height loss of 1.5 in or more from peak height during young adulthood, or of 0.8 in or more from last documented height measurement Recent or ongoing long-term glucocorticoid treatment Medical conditions associated with bone loss (eg, hyperparathyroi...
OGA has two major splice isoforms, long (lOGA) and short (sOGA). Both isoforms are comprised of a glycoside hydrolase 84 (GH84) catalytic domain at the N-terminus and a helical bundle stalk-like domain. However, while lOGA possesses a pseudo-histone acetyltransferase domain (pHAT) in its ...
It requires a long-term treatment. The patient can never be sure that it heals completely. The pathophysiology depends on: (1) the extent of soft tissue damage and impairment of blood supply; (2) inoculation of bacterial flora; (3) the instability of the fracture area; and (4) the ...
H. et al. Effect of dipyridamole and aspirin on late vein-graft patency after coronary bypass operations. N. Engl. J. Med. 310, 209–214 (1984). Article CAS PubMed Google Scholar Bourassa, M. G. et al. Long-term fate of bypass grafts: the Coronary Artery Surgery Study (CASS) and...
These effects lead to a suppression of bone formation, a central feature in the pathogenesis of GIO. Glucocorticoids also favor osteoclastogenesis and as a consequence increase bone resorption. Bisphosphonates are effective in the prevention and treatment of GIO. Anabolic therapeutic strategies are under...
There is total loss of sensitivity of the internal organs in patients with complete transec tion of the spinal cord above thoracic 10 level, and only partial insensitivity when there is injury in addition to fracture at thoracic 12-lumbar 1, with lesions of the spinal cord below thoracic ...
Individuals with NF1 are prone to developing a wide range of osseous and skeletal manifestations, such as macrocephaly, short stature, sphenoid wing dysplasia, scoliosis, congenital pseudarthrosis of the long bones [11,12], increased fracture risk [13], reduced bone mineral density (BMD) or oste...
Furthermore, the review presents future directions in the treatment of ICU-related bone loss. Keywords: bone loss; critical illness; fracture; osteoporosis 1. Introduction Critically ill patients encounter physical symptoms and physiological changes of varying severity and persistence [1]. Compared with...