He coined the term "lipohyalinosis" to describe the microvascular mechanism that engenders small subcortical infarcts in the absence of a compelling embolic source. Since Fisher's early descriptions of lipohyalinosis and lacunar stroke (LS), there have been many advancements in the understanding of...
Pathophysiology of ischemic stroke Cerebrovascular disease includes both ischemic stroke and hemorrhagic stroke. Ischemic stroke may present in the form of thrombotic , embolic , systemic hypo perfusion or venous thrombosis. Acute occlusion of the intracranial artery causes reduced blood flow to the brai...
Stroke is the world's second leading cause of mortality, with a high incidence of severe morbidity in surviving victims. There are currently relatively few treatment options available to minimize tissue death following a stroke. As such, there is a press
Acute ischemic stroke is caused by thrombotic or embolic occlusion of a cerebral artery. (See the image below.) Maximum intensity projection (MIP) image from a computed tomography angiogram (CTA) demonstrates a filling defect or high-grade stenosis at the branching point of the right middle ...
Cerebral ischemia is always vascular origin and can be divided into haemorrhagic and thromboembolic, with the latter accounting for approximately 90% of strokes (Scatton, 1994) and results from embolic or thrombotic occlusion of the major cerebral arteries, most often the middle cerebral artery....
Yamashita M, Oka K, Tanaka K (1983) Histopathology of the brain vascular network in Moya Moya disease. Stroke 14:50–58 Yates PO (1976) Vascular disease of central nervous system. In: Blackwood M, Corsellis JAN (eds) Greenfield’s neuropathology, 3rd edn. Edward Arnold, London, pp 86–...
Veins are the most commonly used conduits for surgical revascularization; however, they are associated with a high failure rate. In this Review, de Vries and colleagues discuss the pathophysiological mechanisms underlying the development of vein graft fa
2023, Annals of Indian Academy of Neurology A score to predict the stroke recurrence of patients with embolic stroke of undetermined source 2022, Journal of Neurology Secondary prevention of ischemic stroke: Laboratory and imaging biomarkers 2021, Therapeutische Umschau Cerebral border zone infarction: an...
The progressive decline of vascular integrity and blood–brain barrier (BBB) function is associated with aging, a major risk factor for stroke. This review describes the cellular and molecular changes in the brain microvasculature of the neurovascular unit (NVU) that contribute to the development of...
care. It underscores the importance of integrating renal considerations into stroke treatment protocols and highlights the need for future research to refine therapeutic strategies, address knowledge gaps, and consider tailored interventions to improve outcomes and quality of life for this high-risk ...