Mostly the manifestation of acute liver disease (e.g., viral hepatitis) is so mild that they never come to medical attention. However the entire liver may be affected in few cases leading to fulminant liver failure, which is a life-threatening condition. In chronic liver disease the symptoms...
Alcohol abuse remains the predominant cause of chronic liver disease in the Western world. The targets of autoantibodies used to diagnose autoimmune diseases of the liver and primary biliary cirrhosis continue to be biochemically defined. Their significance for the aetiology of the disease, however, ...
Endogenous opioids modulate hepatocyte apoptosis in a rat model of chronic cholestasis: the role of oxidative stress Aims/Background: There are increasing number of evidences indicating the contribution of endogenous opioids in the pathophysiology of cholestatic liver dis... Seyedmehdi,Payabvash,Saman,....
Background: Measurement of serum α-fetoprotein (AFP) and abdominal ultrasound (US) examination are used for the early detection of hepatocellular carcinoma (HCC) in chronic liver disease patients. However, the accuracy and usefulness of these tests in a clinical setting in the United States of ...
Pathophysiology of Hepatic Encephalopathy: A New Look at GABA from the Molecular Standpoint Hepatic encephalopathy (HE) is a neuropsychiatric disorder associated with either acute or chronic liver failure. More than two decades ago, the role of al......
Chronic itch associated with systemic diseases continues to be one of the most bothersome dermatological symptoms accompanying end-stage renal disease (ESRD), chronic liver diseases, and lymphoma. The International Forum for the Study of Itch has recently issued a consensus paper on different types of...
- 《Therapeutic Advances in Respiratory Disease》 被引量: 17发表: 2015年 Pulmonary vascular complications of chronic liver disease: Pathophysiology, imaging, and treatment. To review the pathogenesis of pulmonary vascular complications of liver disease, we discuss their clinical implications, and ...
Portal hypertension is a common complication of chronic liver disease. Its relevance comes from the fact that it determines most complications leading to death or liver transplantation in patients with cirrhosis of the liver: bleeding from esophageal or gastric varices, ascites and renal dysfunction, ...
Cirrhosis represents the end stage of any chronic liver disease. Hepatitis C and alcohol are currently the main causes of cirrhosis in the United States. A... G Garcia-Tsao,J Lim - 《American Journal of Gastroenterology》 被引量: 818发表: 2009年 Current management of the complications of por...
Keywords Liver fibrosis Chronic liver disease (CLD) Hepatic stellate cells (HSC) Anti-fibrotic drug Drug development In-vitro models Sorry, something went wrong. Please try again and make sure cookies are enabledReferences [1] M. Pinzani Pathophysiology of liver fibrosis Dig. Dis., 33 (2015),...