New insights into the patho- physiology and therapy of adult acute lym- phoblastic leukemia. Cancer. 2015;121(15): 2517-2528.Jabbour E, O'Brien S, Konopleva M, Kantarjian H. New insights into the pathophysiology and therapy of adult acute lymphoblastic leukemia. Cancer. 2015;121:2517-28....
Methotrexate (MTX) a mainstay of continuation therapy for acute lymphoblastic leukemia is associated with hepatic and neurotoxicity. The metabolism of MTX ... Kamn,N Wnck,C Sr,... - 《Pediatric Research》 被引量: 0发表: 1985年 加载更多研究点推荐 Endogenous Toxins Drug-Mediated Toxicities ...
new insights into the pathophysiology and therapy of adult acute lymphoblastic leukemia 热度: New insights into the pathophysiology of postoperative cognitive dysfunction 热度: New Insights into the Pathoanatomy of Macular Holes Based on Features of Optical Coherence Tomography.[2017][Surv Ophtha.新见解的...
Introduction Acute leukemias very rarely present with jaundice. Herein we report a case of precursor B-cell acute lymphoblastic leukemia that presented wit... MN Siddique,M Popalzai,N Aoun,... - 《Journal of Medical Case Reports》 被引量: 6发表: 2011年 Intestinal barrier dysfunction in obstruct...
A progressive disease that can transform into acute leukaemia. Also known as stem cell leukaemia or lymphoma syndrome, it often presents with a T-cell lymphoblastic lymphoma and eosinophilia. Crouzon's syndrome A craniosynostosis syndrome presenting with a beaked nose and bulging, excessively separated...
acute promyelocytic leukemia; all-trans retinoic acid; arsenic trioxide; coagulopathy; hemorrhage; thrombosis1. Introduction Acute myeloid leukemia (AML) is a hematologic malignancy accounting for approximately 12,000 cases and 9000 deaths annually in the United States [1]. Acute promyelocytic leukemia ...
Those modified cells preferentially target neoplastic cells with increased expression of specific antigens such as CD19, which is overexpressed in B-cell malignancies (such as acute lymphoblastic leukemia and non-Hodgkin lymphoma). CAR-T formulation requires a patient who has undergone leukapheresis, ...
Acute leukemia – Pre-B acute lymphoblastic leukemia (ALL), acute myeloid leukemia M4 with bone marrow eosinophilia (AML-M4Eo) Chronic myeloid disorders Molecularly defined disorders include the following: BCR-ABL chronic myeloid leukemia (CML) PDGFRA (platelet-derived growth factor receptor, alpha...
Expansion and activation of granulocytic, myeloid-derived suppressor cells in childhood precursor B cell acute lymphoblastic leukemia Precursor B cell acute lymphoblastic leukemia (B-ALL) is a B cell-derived, malignant disorder with the highest incidence among children. In addition to the... Yu-feng...
Young children have acute lymphoblastic leukemia of T-cell origin. Older children have T-cell leukemia. The risk for other cancers is increased 4-fold (2-fold to 3-fold increased risk for breast cancer in carriers). Bloom syndrome < 1% of mutations BLM: 15q26.1 UV, cancer chemotherapeutic ...