With a focus on COPD-related pathogenesis, we independently assessed inflammatory response, protease-antiprotease balance, oxidative stress, and apoptosis in both groups. Both groups showed similar pathological changes at a comparable degree of emphysema; the expression of inflammatory factors was ...
Therefore, muscle-specific proteins or miRNAs can be used to evaluate the changes of muscle-derived EVs during exercise. Exercise-induced release of EVs with other contents into the circulatory system may also bring health benefits. Whitham et al. found that the abundance of 322 proteins in EVs...
Methods: Human primary alveolar macrophages were isolated from bronchoalveolar lavages of 50 patients with pulmonary diseases. The expression of ORs was validated using RT-PCR, immunocytochemical staining, and Western blot. Changes in intracellular calcium levels were analyzed in real-time by calcium...
Changes in barometric pressure characterize both high altitude and the underwater world. These changes have a significant impact on the body's pulmonary physiology and can affect both mountain climbers and divers. In both of these conditions, the organism must use compensatory mechanisms to adapt to...