Diseases associated with damage to such vital organs of the digestive system as the liver and pancreas are an urgent problem of world health. Non-alcoholic fatty liver disease (NAFLD) is a worldwide epidemic; the problem of type 2 diabetes (T2D) mellitus becomes more acute every year; hepatoc...
1.The scientific study of the nature of disease and its causes, processes, development, and consequences. Also calledpathobiology. 2.The anatomic or functional manifestations of a disease:the pathology of cancer. 3.A departure or deviation from a normal condition:"Neighborhoods plagued by a self-...
Analysis of liver pathologies in stray dogs in the age aspect (sectional study)doi:10.1051/E3SCONF/202125408027L.V. TkachenkoEDP SciencesE3S Web of Conferences
by Niigata University Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A. Credit: Niigata University In theirDisease Models & Mechanismsstudy, the research group of Professor Kamimura in Niigata University has demonstrated that the autonom...
The ratio of the two sulfur-containing amino acids, methionine (Met) and cysteine (Cys), may be a determining factor for which foods contribute to longevity and health. It is shown here that substantially more Met than Cys is consistently found in foods, such as dairy and meat products, th...
LIVER diseasesAUTOPSYAGE groupsBackground: Silent liver disease is a major cause of morbidity and mortality in the population due to its silent progression to end stage liver disease without significant symptoms. We aim to study pattern of pathological findings and latent forms of di...
We have studied the influence of different hepatic pathologies on the disposition of alfentanil in 23 unpremedicated patients (six healthy control subjects, six patients with liver dysfunction of alcoholic aetiology and 11 patients with non-alcohol related liver disease). All patients received a bolus...
To examine CLCC1 topology in the ER membrane, we treated microsomes prepared from WT mouse cerebella and livers24 with trypsin and analyzed the remaining CLCC1 fragments with our N- and C-terminal antibodies. In the absence of Triton X-100, the N-terminus and the first and second loops of...
Lastly, KRT8 aggregation can be seeded by liver extract from people with ASH, consistent with the amyloid nature of KRT8 aggregates and the classification of ASH as an amyloid-related condition.Similar content being viewed by others CryoEM structure of the low-complexity domain of hnRNPA2 and ...
Targeting the liver clock improves fibrosis by restoring TGF-β signaling 2024, Journal of Hepatology Citation Excerpt : Interestingly, CC regulation of Tgfb1 and Smad3 expression has also been observed in the kidney, adipose tissue and heart.25,26 Genome-wide association studies have implicated dif...