HRDsig(-) patients were more likely to have pCR receiving both platinum Tx (37.0% vs. 4.4%, p<0.001) and non-platinum Tx (23.8% vs. 5.2%, p<0.001). Platinum vs. non-platinum Tx showed a trend towards moderately enriched pCR rates in the HRDsig(+) group (37.0% vs. 23.8%, odds...
Objective: Our primary objective was to make a nomogram to predict the pathologic complete response (pCR) rate in primary HER2-positive breast cancer patients treated with neoadjuvant systemic therapy. Our hypothesis is high HER2 FISH ratio and low ER expression level is associated with high pCR ...
Merck announces phase 3 KEYNOTE-756 trial met primary endpoint of pathological complete response (pCR) rate in patients with high-risk, early-stage ER+/HER2-breast cancer. Merck. News release. July 28, 2023. Accessed July 28, 2023. https://www.merck.com/news/mer...
Accurate prediction of pathological complete response (pCR) to NAC in the early-stage or posttreatment can optimize treatment strategies or improve the breast-conserving rate. This study aimed to develop and validate an autosegmentation-based serial ultrasonography assessment system (SUAS) that ...
This exploratory analysis of the Neoadjuvant Carboplatin in Triple Negative Breast Cancer (NACATRINE) study aimed to identify the biomarkers of pathological complete response (pCR) in patients with triple-negative breast cancer (TNBC) treated with neoadj
(2012) The discrepancy between high pathological complete response (pCR) rate and low breast conserving surgery (BCS) following neoadjuvant therapy: analysis ... C Criscitiello,HA Azim,D Agbor-Tarh,... - Congress of the European-society-for-medical-oncology 被引量: 2发表: 2012年 Radiation ...
pCR: Pathological complete response SG: Sacituzumab govitecan SMI: Standardized mitotic index sTILs: Stromal tumor-infiltrating lymphocytes TNBC: Triple-negative breast cancer TROP-2: Trophoblast cell-surface antigen-2 References De Jong, V. M. T.et al.Prognostic value of tumour infiltrating lymphocy...
Overall survival pCR: Pathological complete response PFS: Progression free survival ROC: Receiver operating curve TMs: Tumor markers References Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality world...
( ACT ).In the NCT plus surgery group, the response rate ( RR = CR + PR ) was 70.3%, pathological complete response ( pCR ) was 5.4%, the ... 郑庆锋,王宇昭,朱赛楠,... - 《中国肿瘤临床》 被引量: 0发表: 2011年 Implications of Pathological Complete Response (pCR) at the Primary...
This study aimed to evaluate if neoadjuvant immune checkpoint inhibitor (ICI) plus chemotherapy (CT) reduced tumor recurrence after surgery than neoadjuvant CT alone in non鈥搒mall cell lung cancer (NSCLC) patients with pathologic complete response (pCR).#From January 1st 2019 to April 30th 2022,...