In human diseases, free heme has been implicated as a harmful medi- ator in sickle cell disease (SCD) [23–27], malaria [14,28,29], sepsis [30], acute lung injury (ALI) [31,32] acute kidney injury (AKI) [33–35], and other inflammatory conditions. Heme is...
In vivo, TNT-like protrusions called cytonemes have been observed in the imaginal disc development of Drosophila [136,137] and in the midgut of the Anopheles malaria vector prior to the fertilization of Plasmodium gametes [138]. Only recently have other examples of TNT-like structures observed ...
and MERS-CoV SARS-CoV-2 RNA viruses and SARS-CoV-2 SARS-CoV-1 and SARS-CoV-2 Influenza and SARS-CoV-2 Reduces the rate of replication Malaria, systemic inflammatory diseases, and SARS-CoV-2 Inhibition of glycosylation of host receptors, proteolytic processing, and acidification of endosomes ...