The Pathogen鈥揌ost Interactions Database (PHI-base) has, since 2005, provided manually curated genes from fungal, bacterial and protist pathogens that have been experimentally verified to have important pathogenicity, virulence and/or effector functions during different types of interactions involving ...
PHI-base also curates lit-erature describing specif i c gene alterations that didnot affect the disease interaction phenotype, in or-der to provide complete datasets for comparativepurposes. Viruses are not included, due to their ex-tensive coverage in other databases. In this article,we ...
HPIDB 2.0: a curated database for host-pathogen interactions. Database (Oxford). 2016;2016:1–9. Article Google Scholar Licata L, Briganti L, Peluso D, Perfetto L, Iannuccelli M, Galeota E, et al. MINT, the molecular interaction database: 2012 Update. Nucleic Acids Res. 2012;40:857...
PHI-base update: Additions to the pathogen-host interaction database The pathogen鈥揾ost interaction database (PHI-base) is a web-accessible database that catalogues experimentally verified pathogenicity, virulence and effec... R Winnenburg,M Urban,A Beacham,... - 《Nucleic Acids Research》 被...
interactions: To predict new interactions, each PPI from the query dataset was inspected the following way: the host protein in the query PPI was searched against all the pairwise comparisons in the positive database of similar proteins and whenever a match was found, the query interaction was ...
Our results show that our approach outperforms the baselines on the training data. We further analyze the protein interaction predictions generated by the models, and find some interesting insights. 展开 关键词: INTERACTION PREDICTION INTERACTION DATABASE GENE ONTOLOGY CLASSIFICATION FRAMEWORK NETWORK ...
For predicting the pathogen-host protein interactions, BLASTP (https://blast.ncbi.nlm.nih.gov/Blast.cgi?PAGE=Proteins) was performed with the help of Host Pathogen Interaction Database (HPIDB) v2.0103and Biana Interolog Prediction Server (BIPS)104against all known pathogen-host protein interaction...
RNA-seq data profile of pitaya and N. dimidiatum To investigate the gene expression characteristics during the dynamic infection of N. dimidiatum in pitaya, we conducted RNA-seq analysis to examine the dynamics of the interaction between pitaya and N. dimidiatum. Healthy pitaya and N. dimi...
These data may have great and immediate practical values. In fact, small molecules that directly target NPC1 and disrupt GP binding are regarded as possible therapeutic compounds against EBOV82–84 (FIG. 4). Because mammalian NPC1 diversity at the interaction surface is driven by selection, ...
‘bacterial extracellular solute-binding protein’, ‘porin’, ‘invasin’, ‘fibronectin-binding protein’, ‘transferrin-binding protein’, ‘virulence’, ‘penicillin-binding protein’, ‘flagellin’, ‘colonization’, ‘host-pathogen interaction’ and ‘toxin’ to identify domains from each classes...