nocturnal paroxysmal hemoglobinuria夜间阵发性血红蛋白尿症 paroxysmal nocturnal hemoglobinuria阵发性睡眠性血红蛋白尿,阵发性夜间血红蛋白尿 nocturnal hemoglobinuria夜间血红蛋白尿 paroxysmal hemoglobinuria阵发性血红蛋白尿症 paroxysmal cold hemoglobinuria阵发性寒冷性血红蛋白尿症 ...
Paroxysmal nocturnal hemoglobinuria occurs due to the development of a genetic mutation in hematopoietic stem cells. This mutation of the X-linked gene phosphatidylinositol glycan class A (PIGA), produces a deficiency in the glycosylphosphatidylinositol (GPI) protein, which is responsible for anchoring ...
nocturnal paroxysmal hemoglobinuria夜间阵发性血红蛋白尿症 paroxysmal nocturnal hemoglobinuria阵发性睡眠性血红蛋白尿,阵发性夜间血红蛋白尿 nocturnal hemoglobinuria夜间血红蛋白尿 paroxysmal hemoglobinuria阵发性血红蛋白尿症 paroxysmal cold hemoglobinuria阵发性寒冷性血红蛋白尿症 ...
Related to paroxysmal nocturnal hemoglobinuria:Paroxysmal cold hemoglobinuria he·mo·glo·bi·nu·ri·a (hē′mə-glō′bə-no͝o′ē-ə, -nyo͝or′-) n. The presence of hemoglobin in the urine. he′mo·glo′bi·nu′ricadj. ...
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and complex disease caused by clonal expansion of hematopoietic stem cells that have acquired a somatic, loss-of-function mutation in the phosphatidylinositol glycan anchor biosynthesis, class A gene. The blood cells generated by such a clone lack ...
“Paroxysmal nocturnal hemoglobinuria.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/paroxysmal%20nocturnal%20hemoglobinuria. Accessed 16 Aug. 2024. Copy Citation Share Post the Definition of paroxysmal nocturnal hemoglobinuria to Facebook Facebook ...
Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria Pulmonary hypertension in paroxysmal nocturnal hemoglobinuria Natural History of Paroxysmal Nocturnal Hemoglobinuria — NEJM Effect of Eculizumab on Hemolysis and Transfusion Requirements in Patie...
概述 阵发性睡眠性血红蛋白尿(paroxysmal nocturnal hemoglobinuria,PNH)系后天获得性的红细胞膜缺陷引起的对补体激活异常敏感的慢性血管内溶血,常睡眠时加重,可伴间歇性血红蛋白尿和全血细胞减少症或反复血栓形成。 病因和发病机制 PNH 是由于红细胞
Related to paroxysmal nocturnal hemoglobinuria: Paroxysmal cold hemoglobinuriahemoglobinuria [he″mo-glo″bĭ-nu´re-ah] the presence of free hemoglobin in the urine. adj., adj hemoglobinu´ric. march hemoglobinuria hemolysis caused by repeated uncushioned shocks or trauma to some body part, ...
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired stem cell disorder (incidence of 2–6 per million) characterized by hemolytic anemia, marrow failure and thrombosis. It is due to a mutation in the phosphatidylinositol glycan class A (PIG-A) gene, which results in a deficiency of gl...