作者:Leader, Lucille; Leader, Geoffrey; 出版年:2009-5 页数:52 定价:$ 22.60 ISBN:9780952605669 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到 内容简介· ··· PARKINSONS DISEASE DOPAMINE METABOLISM, APPLIED BIOCHEMISTRY and NUTRITION Authors: Lucille Leader and Dr Geoffrey Leader ...
帕金森病(Parkinson’s disease,PD)是一种常见的神经系统变性疾病,老年人多见,平均发病年龄为60岁左右,40岁以下起病的青年帕金森病较少见。 帕金森病最主要的病理改变是中脑黑质多巴胺(dopamine, DA)能神经元的变性死亡,由此而引起纹状体DA含量显著性减少而致病。 要明白帕金森病的治病原理,首先要了解以下几个概念:...
Parkinson's disease is a movement disorder characterized by degeneration of dopamine-producing neurons. At early stages, pharmacological replacement treatment with dopamine receptor agonists or the dopamine precursor, L-DOPA, can cause symptomatic relief. However, ultimately these treatments are insufficient...
帕金森病(英语:Parkinson's Disease) 帕金森病(英语:Parkinson's Disease)或译巴金森氏病,台湾译作帕金森氏症,港澳译作柏金逊症,是一种慢性的中枢神经系统退化性失调,它会损害患者的动作技能、语言能力以及其他功能。它的病因目前仍不明,推测和大脑底部基底核(basal ganglia)以及黑质(substantial nigra)脑细胞快速...
摘要: 帕金森病(Parkinson’s disease,PD)是仅次于阿尔茨海默病的第2大神经退行性疾病。目前,有效治疗PD的主要途径是服用左旋多巴,但是,长时间服用左旋多巴会导致一系列副作用,如运动障碍、恶心、失眠、疗效减退、“开关”现象等。沙芬酰胺于2017年3月21被美国FDA批准用于治疗PD,作为治疗PD的新型药物,具有选择性高...
Parkinson’s disease is a progressive condition characterized by a gradual loss of neurons that normally produce the neurotransmitter dopamine, leading to problems with movement control and non-movement-related symptoms. Parkinson's disease overview ...
Parkinson’s disease (PD) is a degenerative, progressive disorder that affects nerve cells in deep parts of the brain called the basal ganglia and the substantia nigra. Nerve cells in the substantia nigra produce the neurotransmitter dopamine and are responsible for relaying messages that plan and ...
Parkinson's disease is linked to abnormalities in the levels of dopamine in the body. The structure of dopamine is
When these neurons die, abnormally low levels of dopamine are produced. This makes it difficult to control muscle tension and muscle movement.Having a parent or sibling diagnosed with the disease at a younger age increases your risk of getting PD. The same is not true if the affected family ...
Parkinson’s disease is a neurodegenerative disease caused by the death of neurons, ie, cells critical to the production of dopamine, an important neurotransmitter in the brain. Here, we present a brief review of the dopamine synthetic pathway, binding to the dopamine receptors, and subsequent act...