gatha Oliveira-GiacomelliC.M. AlbinoHellio Danny Nóbrega de SouzaHenning UlrichGenetics, Neurology, Behavior, and Diet in Parkinson's Disease
doi:10.1016/0006-3223(90)90108-E
This article reviews the role of the D1-like dopamine receptors in Parkinson's disease (PD), an idea supported by the location of D1 receptors in key aspects of basal ganglia circuitry. The initial disappointing results with available partial D1 agonists have been replaced by optimism as newer...
Parkinson's disease is a movement disorder characterized by degeneration of dopamine-producing neurons. At early stages, pharmacological replacement treatment with dopamine receptor agonists or the dopamine precursor, L-DOPA, can cause symptomatic relief. However, ultimately these treatments are insufficient...
DISEASE DOPAMINE METABOLISM, APPLIED BIOCHEMISTRY and NUTRITION Authors: Lucille Leader and Dr Geoffrey Leader Foreword: by Dr Nicholas Miller This user-friendly monograph illustrates the various metabolic pathways implicated in Parkinsons disease, with their primary sources in protein, carbohydrates and ...
Parkinson's disease psychosis (PDP) is theoretically a serotonin-dopamine imbalance syndrome due to disruption of the normal balance between the serotonergic and dopaminergic neurotransmitter systems in key brain circuits.DOI: 10.1017/s1092852916000602 年份...
Levodopa is the gold-standard therapy for Parkinson's disease. However, long-term treatment leads to involuntary movements and response fluctuations which add to the complexities of later disease-management. In addition, preclinical evidence suggests that levodopa is toxic to dopaminergic neurons. These...
a焊接用电弧焊 The welding uses electricity the arc welding[translate] aThe decrease in the amount of dopamine can result in one or more general signs of Parkinson’s disease 在数量的 dopamine 方面的减少可以导致帕金森氏症的一个或多个一般标志[translate]...
Plante-Bordeneuve V, Taussig D, Thomas F, Said G, Wood NW, Marsden CD, Harding AE: Evaluation of four candidate genes encoding proteins of the dopamine pathway in familial and sporadic Parkinson’s disease: Evidence for association of a DRD2 allele. Neurology 1997;48:1589–1593. External ...