AHC MEDIANeurology Alert
Genetic risk and plasma biomarkers of dementia with Lewy bodies in a Chinese population Xiaoli Hao Xuewen Xiao Lu Shen ArticleOpen Access15 May 2025 Differential memory enrichment of cytotoxic CD4 T cells in Parkinson’s disease patients reactive to α-synuclein ...
Some treatments that are approved for dementia in Alzheimer’s, particularly donepezil and galantamine, also may help to manage dementia in Parkinson’s patients. For depression and anxiety, treatments for those with Parkinson’s generally are similar in nature to strategies used for other people ...
Aggregates of misfoldedα-synucleinand otherproteins, such asubiquitinandneurofilamentprotein within the neural cell bodies Appear histologically as intracellularhyalineeosinophilic globules May befound inbrainstem,substantia nigra, and cortex[6] Also seen inLewy body dementia ...
Alzheimer's disease & dementia Novel antibody discovery platform may inform Alzheimer's and Parkinson's research In diseases like Parkinson's and Alzheimer's, specific proteins misfold and clump together, forming toxic aggregates that damage brain cells. The process of proteins spontaneously clumping ...
Parkinson’s disease-dementia PET: Positron emission tomography PSEN1: Presenilin 1 p-tau: Phosphorylated tau RBD: REM sleep behavior disorder SN: Substantia nigra SNc: Substantia nigra pars compacta SNCA: α-Synuclein gene SPECT: Single-photon emission computed tomography ...
BehaviorTreatmentParkinsonDementiaNursing homeLong‐term carePharmaco‐epidemiologyHubert H. FernandezDepartment of Clinical Neurosciences, Brown University, Providence, Rhode Island, U.S.A.Kate L. LapaneCenter for Gerontology and Health Care Research, Brown University, Providence, Rhode Island, U.S.A....
Changes in motor subtype and risk for incident dementia in Parkinson's disease. Mov. Disord. 21, 1123–1130 (2006). Article PubMed Google Scholar Churchyard, A. & Lees, A. J. The relationship between dementia and direct involvement of the hippocampus and amygdala in Parkinson's disease. ...
of females (CI-PD: 54.2%, nCI-PD: 26.2%,P = 0.013), compared to the nCI-PD group, and a significantly lower level of ethanol consumption than the nCI-PD group (Fig.4e, f). There was no significant difference between the groups in the prevalence of dementia at the final ...
PD dementia Sleep disorders REM sleep behavior disorder Restless legs syndrome Periodic limb movements of sleep Excessive daytime somnolence Insomnia Mood disorders Depression Anxiety/panic attacks Pain and sensory disorders Pain Paresthesias Limb pain Joint pain Visceral pain Olfactory dysfunction Loss of...