The authors report on the structures of α-synuclein filaments from the brains of individuals with Parkinson's disease, Parkinson's disease dementia and dementia with Lewy bodies and how they differ from those seen in multiple system atrophy. ...
PARKINSON'S DISEASE AND DEMENTIA. By - A.J. Leesdoi:10.1016/S0140-6736(85)90986-9LEESAElsevier Ltd.LancetLees AJ: Parkinson’s disease and dementia. Lancet, vol 1, 43–44. 1985. View ArticleLees A, Parkinson’s disease and dementia, 1985, Lancet , 1:43–44....
Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from the brainstem to limbic and neocortical structures seems to be the strongest neuropathological correlate of emergi...
Parkinson diseaseDementiaLewy bodiesAlzheimer diseaseCognitive functioningNeuroimagingParkinson鈥檚 disease (PD) is one of the most common neurodegenerative disorders, affecting about 1% of the population over the age of 60. In addition to motor abnormalities, there are several non-motor signs and ...
Dementia is a common problem in Parkinson's disease (PD) that can be divided into Parkinson's disease with dementia (PDD) and dementia with Lewy bodies (DLB). This is based on the chronologic sequence of the development of these problems, but the two conditions do not differ in any ...
Parkinson's disease with dementia and dementia with Lewy body disease: two syndromes, the same disease? Psychogeriatrics, 6: S30-S34Sellal, F.: Parkinson's disease with dementia and dementia with Lewy body disease: two syndromes, the same disease? Psychogeriatrics 6 (2006) 30-34...
Dementia affects about 40% of patients with Parkinson's disease; the incidence of dementia in these patients is up to six times that in healthy people. Clinically, the prototype of dementia in PD is a dysexecutive syndrome. Loss of cholinergic, dopaminergic, and noradrenergic innervation has been...
Anthony: Jules, you do whatever you want and trust your instincts. I left the farm to you so it is your decision. Me: Thanks Ants. I miss you so much…. Anthony: I will applaud you, whatever you decide, Jules. Alzheimer's Disease; DementiaAnthonyAnxietydeathdeath and dyingdementiadepress...
Dementia with Lewy bodies (DLB) and Parkinson’s disease-dementia (PDD), although sharing many clinical, neurochemical and morphological features, according to DSM-5, are two entities of major neurocognitive disorders with Lewy bodies of unknown etiology. Despite considerable clinical overlap, their di...
Kashihara, K., Ohno, M., Kawada, S. & Okumura, Y. Reduced cardiac uptake and enhanced washout of 123I-MIBG in pure autonomic failure occurs conjointly with Parkinson’s disease and dementia with Lewy bodies.J. Nucl. Med., 1099–1101 (2006). ...