Parathyroid hormone has dual effects on bone cells, stimulating both bone resorption and bone formation. Almost all of the known effects of PTH on bone cells appear to be mediated through the PTH1 receptor (PTHR1). PTHR1 is found on several different cell types, including osteoblasts, ...
Target Cell Responsiveness to Parathyroid Hormone. Physiologic responses to PTH depend not only on the concentration of PTH in blood but also on the responsiveness of target cells to PTH. This responsiveness can be modified by previous exposure to PTH or by exposure to a variety of other hormone...
hormone: Parathormone of the parathyroid gland PTH has multiple actions, all of which result in an increase in serum calcium concentration. For example, it activates large bone-dissolving cells calledosteoclaststhat mobilize calcium frombonetissue, and it stimulates thekidneytubulesto reabsorb calcium ...
Target Cell Responsiveness to Parathyroid Hormone. Physiologic responses to PTH depend not only on the concentration of PTH in blood but also on the responsiveness of target cells to PTH. This responsiveness can be modified by previous exposure to PTH or by exposure to a variety of other hormone...
Parathyroid hormone has dual effects on bone cells, stimulating both bone resorption and bone formation. Almost all of the known effects of PTH on bone cells appear to be mediated through the PTH1 receptor (PTHR1). PTHR1 is found on several different cell types, including osteoblasts, osteoclas...
423,424 Interestingly, constitutive activation appears to result predominantly in excessive Gαs activity because adenylyl cyclase activity is increased and PLC activity is unchanged in COS-7 cells expressing mutated receptors.423-425 Show moreView chapterExplore book Parathyroid Hormone/Parathyroid Hormone...
parathyroid hormone-related peptidePTHrPX-gal stainingTumor stem or initiating cells have been proposed to exist for melanoma. Stem-like cells have been ... SE Zabierowski,M Herlyn - 《Cancer Cell》 被引量: 71发表: 2008年 Current Treatment Options for Malignant Melanoma parathyroid hormone relate...
Parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHRP) regulate Na+/H+ exchanger activity in osteoblastic cells, although the signaling components involved are not precisely defined. Since these peptide hormones can stimulate production of diverse second messengers (i.e. cAMP and dia...
编 号包装库存目录价(￥)您的价格(￥)数量 C521765-001010 UG预计10日内发货882882 C521765-005050 UG预计10日内发货26462646 产品描述 概述 Recombinant Human Parathyroid Hormone is produced by our E.coli expression system and the target gene encoding Ser32-Gln115 is expressed. ...
Human parathyroid hormone (hPTH) is a key regulator of calcium homeostasis. The hormone is produced as a 115 amino-acid prepro-peptide. Before secretion the prepro part is cleaved off, yielding the 84 amino acid mature hormone. Through its action on target cells in bone and kidney tubuli,...