Aims Acute drug overdose, especially with paracetamol, may cause acute liver failure leading to registration for transplantation (ALFT). Population statistics and between-country differences for ALFT related to overdose have been poorly described. The aim of the present study was to evaluate overdose ...
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Available online: https://www.drugabuse.gov/drug-topics/trends-statistics/overdose-death-rates (accessed on 5 June 2021). 10. Qaseem, A.; McLean, R.M.; O'Gurek, D.; Batur, P.; Lin, K.; Kansagara, D.L. Nonpharmacologic and Pharmacologic Management of Acute Pain From Non-Low Back...
However, overdose and chronic use of PCT produce an accumulation of toxic metabolites that can lead to kidney and liver failure [2,3]. Furthermore, PCT arrives in the environment through sewage plant effluents, sewage sludge, hospital wastewater, surface water, and drinking water [4]. All of...
This study examined the protective effect of flaxseed lignans on liver damage caused by an overdose of paracetamol (PAM). The findings demonstrated that administering 800 mg/kg/d flaxseed lignan prior to PAM significantly decreased the serum aspartate aminotransferase (AST), alanine aminotransferase (AL...