Pancreatic cancer is the fourth leading cause of cancer deaths in the US and typically affects older individuals in the sixth to eighth decades of life. Underlying risk factors include smoking, obe...
Liver macrophage subsets differentially regulate metastasis in pancreatic cancerSupported by grants from NIH (T32 HL0439, F30 CA257287, R01 CA245323)The Journal of Immunology
alung cancerthat travels to theliveris not a "liver cancer" but is described as metastatic lung cancerand a patient with abreast cancerthat spreads to the brain is not described as having a "brain tumor" but rather as having metastatic breast cancer. ...
Pancreatic cancer is one of the most fatal cancers in humans. While it thrives in a state of malnutrition, the mechanism by which pancreatic cancer cells adapt to metabolic stress through metabolic reprogramming remains unclear. Here, we showed that UBR5
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most common cancer in men and the seventh most common in women, but it is the fourth leading cause of cancer deaths in men and the third leading cause in women; it accounts for about 3% of all cancers in the United States but is responsible for about 8% of all cancer-related deaths....
Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a potential curative approach for PC, but most patients are unsuitable for operations when at the time of diagnosis. Even with surgery, some patients may still experienc
Gemcitabine treatment has significantly improved the median survival time of patients with advanced pancreatic cancer (7). However, the outcome of the treatment varies significantly among individuals, and a considerable portion of patients do not appear to benefit significantly from it. It therefore ...
Pancreatic cancer ranks 10th in the incidence rate of malignant tumors in male, and 12th in female. Pancreatic cancer is the sixth leading cause of tumor-r
Cumulative studies have established the significance of transfer RNA-derived small RNA (tsRNA) in tumorigenesis and progression. Nevertheless, its function and mechanism in pancreatic cancer metastasis remain largely unclear. Here, we screened and identi