Pancreatic cancer arising at the caudal side of the pancreas head may sometimes invade the right and left hepatic arteries (RLHA) as well as the CHA. Pancreatic cancer with RLHA involvement may be assessed as u
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However, it is important to note that this observation was made in a model in which PDAC lines were coinjected with cancer-associated fibroblasts39. Several reports showed that the stroma compartment of PDAC can affect the TME; therefore, the coinjection approach may alter the involvement of ...
Pancreatic cancer is the fourth leading cause of cancer deaths in the US and typically affects older individuals in the sixth to eighth decades of life. Underlying risk factors include smoking, obe...
Healthy pancreas help to balance chemicals that support digestion. Its healthy function, especially regulating your blood sugar, is critical for your kidney, liver, digestive, brain, and overall health. However, a lot can go wrong with your pancreas. Pancreatic cancer is one of the significant he...
The aim of this study was to identify novel lymphatic metastasis-associated markers and therapeutic targets for pancreatic cancer. Methods: DNA microarray study was carried out to identify genes differentially expressed between 17 pancreatic cancer tissues with lymph node metastasis and 17 pancreatic ...
Pancreatic cancer (PC) is a malignancy of gastrointestinal tract threatening the life of people around the world. In spite of the advances in the treatment of PC, the overall survival of this disease in advanced stage is less than 12%. Moreover, PC cells
Cell Communication and Signaling (2022) 20:1 https://doi.org/10.1186/s12964-021-00806-y REVIEW Open Access Small extracellular vesicles: from mediating cancer cell metastasis to therapeutic value in pancreatic cancer Wenjie Zhang1†, Juan Xing1†, Tian Liu1†, Jie Zhang1,...
The ever-growing perception of cancer stem cells (CSCs) as a plastic state rather than a hardwired defined entity has evolved our understanding of the func
Pancreatic cancer is a common malignant tumor with poor prognosis. Recently, cancer stem cells (CSCs) were identified in several solid tumors, including pancreatic cancer. Although accumulating evidence indicates that sirtuin 1 (SIRT1) exerts biological