Griffith, Y.P. Shao, et al. 2018. Pancreatic and bile duct cancer circulating tumor cells (CTC) form immune-resistant multi-cell type clusters in the portal venous circulation. Cancer Biol. Ther. 19:887-897. https://doi.org/10.1080/15384047.2018.1480292...
Bilirubin is one part of a substance called bile. Your liver makes bile to help you digest your food, especially fats. As pancreatic cancer grows, it often blocks the duct that releases bile into your intestine. Since the bile can't pass through this blocked duct, bile can't get to your...
How is pancreatic cancer diagnosed?Your healthcare provider will examine you and ask about your symptoms. He or she may ask if you have a family history of pancreatic cancer. You may need any of the following:Ultrasound, CT, or MRI pictures will show the location and size of the cancer....
Pancreatic cancer starts in the pancreas. The pancreas is located just behind the stomach. It helps digest food by making enzymes. The pancreas also makes hormones, such as insulin, to help balance blood sugar levels. WHILE YOU ARE HERE: ...
Pancreatic cancer is typically detected at an advanced stage, and is refractory to most forms of treatment, contributing to poor survival outcomes. The incidence of pancreatic cancer is gradually increasing, linked to an aging population and increasing rates of obesity and pancreatitis, which are risk...
Pancreatic cancer is the fourth leading cause of cancer deaths in the US and typically affects older individuals in the sixth to eighth decades of life. Underlying risk factors include smoking, obe...
Finally, immunotherapy utilizes the patient’s own immune system to combat the cancer; for example, by increasing anti-tumor messenger molecules or blocking a receptor that increases the growth of cells.11 In this protocol you will learn about pancreatic cancer, its potential causes and known ...
cancer cells (which are inherently less adaptable) often respond markedly to inactivation of their addictive pathway. The potent implication of this abnormal characteristic of cancer cells is that blocking of the crucial cascade upon which they rely should have deleterious effects on the mutated cells...
-bile stasis contributes to supersaturation gallbladder with cholesterol-May stay in gallbladder or move to cystic or common bile duct and cause obstruction—> can block bile (gland colored stool) & pain is worse with food) Cholecystitis inflammation of the gallbladder-stone is blocking something ...
Targeted therapy uses the concept of killing the tumor by the use of drugs that attack specific abnormalities present within the cancer cells. These drugs arrest the growth of cancer cells by blocking the mutation that converts normal cells into a cancerous one. Some of the drugs also work by...