including skin, lung, intestine and pancreas.151,152,153,154,155,156,157In parallel to the immune memory, epithelial cells set long-term memory based on epigenetic modifications they have adopted during injury,
especially small RNA molecules such as classical oncogenic miR-21, miR-155, and anti-oncogenic miRNAs like miR-146a and miR-34a, which are differentially expressed between tumor cells and non-tumor cells, enabling them to diagnose multiple cancers at an early-stage, like pancreas, colorectum, ...
来源期刊 Pathology - Journal of the RCPA October 2014 研究点推荐 MUCIN-PRODUCING BILE DUCT TUMOR Hepatobiliary/Pancreas Pathology mucinproducing intraductal papillary neoplasm mucinous cystic neoplasm of the liver (MCN) MUCINOUS CYSTIC TUMOR 0
KEIICHI K,YASUNI N,FUKUO K,et al.Clinicopathologicalfeatures and prognosis of mucin-producing bile duct tumorand mucinous cystic tumor of the liver:a multi-institutionalstudy by the Japan Biliary Association[J].J HepatobiliaryPancreat Sci,2014,21(3):176-185....
Since cAMP signaling regulates cell proliferation and differentiation, abnormal cAMP biogenesis is involved in tumorigenesis, a complex disease resulting from diverse environmental and genetic factors [11]. cAMP has a significant impact on both cancer cells and the tumor microenvironment (TME). Cytokines...
To our knowledge, transgenic mice that over- express AR and HB-EGF in the kidney have not been reported, however, transgenic mice that overexpress AR or HB-EGF in the pancreas demonstrate abnormal proliferation of ductal ep- ithelium (25,26). Similarly, mice that overexpress EGFR in the ...
Am J Transl Res From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis 33841664 Biochem Cell Biol Formononetin protects against concanavalin-A-induced autoimmune hepatitis in mice through its anti-apoptotic...
Am J Transl Res From hair to pancreas: transplanted hair follicle mesenchymal stem cells express pancreatic progenitor cell markers in a rat model of acute pancreatitis 33841664 Biochem Cell Biol Formononetin protects against concanavalin-A-induced autoimmune hepatitis in mice through its anti-apoptotic...
10. Yamaguchi H, Inoue T, Eguchi T, et al Fascin overexpression in intraductal papillary mucinous neoplasms (adenomas, borderline neoplasms, and carcinomas) of the pancreas, correlated with increased histological grade. Mod Pathol 2007;20:552–561. 11. Pelosi G, Pastorino U, Pasini F, et al...
It has been found that a distinct group of cell surface antigens is expressed on several human cancer cells, especially on human pancreas cancer cells, but not or to a lower level on non-malignant cells. Accordingly, these antigens (also referred to as “markers”) can be used to identify...