Ambrogi F, Fornili M, Alberti S, Querzoli P, Piantelli M, Pedriali M, et al .: EpCAM expression is an indicator of increased incidence of relapse in p53-positive breast cancer. Cancer Clin Oncol 2013, 2 : 41-50.Ambrogi F, Fornili M, Alberti S, Querzoli P, Piantelli M, Pe...
In this study of 7226 Chinese women with invasive breast cancer, we defined breast cancer subtypes using immunohistochemical (IHC) measures of hormone receptors and HER2 in conjunction with histologic grade. p53 expression status was then used to further stratify subtypes into p53-positive and p53-...
We found that 57% of these carcinomas expressed high levels of p53 protein (positive nuclear staining). Survival analysis revealed a strong association between p53 status of the tumour and patient survival time after diagnosis (p = 0.02, Mantel-Cox Test); odds ratio of death, 2.09 (95% ...
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[10] Grassadonia A, Di Nicola M, Grossi S, et al. Long-term outcome of neoadjuvant endocrine therapy with aromatase inhibitors in elderly women with hormone receptor-positive breast cancer[J]. Ann Surg Oncol, 2014, 21...
The TP53 mutation frequency is higher in node-positive breast cancer [4]. In addition, some studies have claimed a prognostic and or predictive value for TP53 in relation to different cytotoxic agents and tamoxifen [5., 6., 7., 8.], while other studies have failed to demonstrate such ...
Her2: HER2-positive. LumA: Luminal A. LumB: Luminal B. Normal: Normal breast-like. p values were calculated by comparing expression means across all subtypes. LFNG Low Expression is Associated with Poor Survival in Human Breast Cancer Given that LFNG expression was down-regulated in human BLBC...
LOHrateissignificantbetweenthepositiveandnegativeaxillarylymphnodemetastatictumors(P<0.05).Theresultsindicated thatp53mutationwasanearlyeventinthecourseofbreasttumorandpredictedaintenseaggressionoftumorcell,whichwould thenrapidlyprogressthroughearlystage. KeywordsBreastcancerp53Mutation 肿瘤的形成是由癌基因和抗癌基因构成...
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The value of Ki67 in very young women with hormone receptor-positive breast cancer: retrospective analysis of 9,321 Korean women. Annals of surgical oncology 22, 3481–3488 (2015). Article Google Scholar Li, L. T., Jiang, G., Chen, Q. & Zheng, J. N. Ki67 is a promising molecular...