5.Immunohistochemical staining with deltaNp63 is useful for distinguishing the squamous cell component of adenosquamous cell carcinoma of the lung.[J].Yamada S;Uramoto H;Hanagiri T,Anticancer Research: International Journal of Cancer Research & Treatment.2010,第11期 ...
RESULTS: Using TMA analysis, the napsin A-positive (1)/p40 +/- immunophenotype identified ACA with 94% sensitivity and 100% specificity, whereas the napsin A (negative)-/p40+ immunophenotype identified SQCC with 100% sensitivity and specificity. On the validation cohort of 80 cell block and ...
lung squamous cell carcinoma were analyzed.Results The positive expression rates of CK5/6and P40in lung squamous cell carcinoma specimen were higher than those in lung adenocarcinoma specimen (P <0.05).There were no significant differences in the sensitivity,positive predictive value and negative ...
Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Δ Np73L, a novel dominant-negative... We have recently identified a second p53 -related p73L gene, also referred to as p63/p51/p40/KET gene, which encodes the 2 ...
Dominant negative p63 isoform expression in head and neck squamous cell carcinoma. Laryngoscope 2004;114: 2063–2072. 34 Massion PP, Taflan PM, Jamshedur Rahman SM, et al. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res 2003;63:7113–...
Senoo M, Tsuchiya I, Matsumura Y et al (2001) Transcriptional dysregulation of the p73L/p63/p51/p40/KET gene in human squamous cell carcinoma: expression of ∆Np73 L, a novel dominant-negative isoform, and loss of expression of the potential tumour suppressor p51. Br J Cancer 84:1235–...
that the direct administration of recombinant p40 monomer to RAW 264.7 cells and primary lung macrophages stimulated the production of both pro-inflammatory (TNFα) and anti-inflammatory (IL-10) signals. Accordingly, p40 monomer prevented the full pro-inflammatory effects of LPS, and the neutralizati...
(as negative control). RNA was purified and treated with DNAse to remove genomic DNA. SYBR Green Real-time qPCR was performed as described above using NEAT1 primers and primers for U1 RNA, the binding partner for the positive control SNRNP70. The yield (% input) and specificity (fold ...
Methods By using immunohistochemical SP method for detection of expression of CK protein in NSCLC patients with negative routine pathological examination for the presence of micrometastasis in hilar and mediastinal lymph nodes,and the evaluation of significance of CK expression in lymph nodes with micro...
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