·positivecases.25werepositiveand6werenegativeforTTF一1.Conclusions Thesensitivityandspecificityof 400expressionarewellofrdiagnosinglungsquamouscellcarcinomas.Combineddetectionof400andIYrF一1isvaluabletodistinguish poorlydifferentiatedlungadenoearcinomasfrom squamouscellcarcinomas. Keywords:lungneoplasms;squamouscell...
RESULTS: Using TMA analysis, the napsin A-positive (1)/p40 +/- immunophenotype identified ACA with 94% sensitivity and 100% specificity, whereas the napsin A (negative)-/p40+ immunophenotype identified SQCC with 100% sensitivity and specificity. On the validation cohort of 80 cell block and ...
lung squamous cell carcinoma were analyzed.Results The positive expression rates of CK5/6and P40in lung squamous cell carcinoma specimen were higher than those in lung adenocarcinoma specimen (P <0.05).There were no significant differences in the sensitivity,positive predictive value and negative ...
MEM cases were always negative for all biomarkers. The HS-guided assessment of p40 allowed an effective orientation among thoracic malignancies at the level of individual tumor patients thereby contributing to prospectively realize a driver, holistic approach to cancer characterization. ...
Dominant negative p63 isoform expression in head and neck squamous cell carcinoma. Laryngoscope 2004;114: 2063–2072. 34 Massion PP, Taflan PM, Jamshedur Rahman SM, et al. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res 2003;63:7113–...
p40、CK56、NapsinA联合CT对晚期非小细胞肺癌的分型诊断效能 细胞肺癌疗效及血清肿瘤标志物的影响［Ｊ］．肿瘤基础与临床，２０１８，３１（０６）：５０７－５０９．ＺＨＡＩＬＧ，ＨＵＤＸ．Ａｐａｔｉｎｉｂｃｏｍｂｉｎｅｄｗｉｔｈｐａｃｌｉｔａｘｅｌａｎｄｃａｒｂｏ ｐｌａｔｉｎｉｎｔｈｅｔｒｅａｔｍｅｎｔｏｆ...
- 《British Journal of Cancer》 被引量: 88发表: 2001年 Transcriptional dysregulation of the p73L/p63/p51/p40/KET gene in human squamous cell carcinomas : Expression of ΔNp73L,a novel dominant-negative isoform,... We have recently identified a second p53-related p73L gene, also referred ...
Individual sections received either a set volume of primary antibody solution or an equal volume of CAS Block (negative control). Slides were incubated overnight at 4°C in a humidified chamber. Primary antibody solution was removed and sections washed with PBS. All tissue sections, including ...
Ovalbumin (OVA) was used as a negative treatment control. Next, we used 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) assay to determine whether or not Sjp40 has an inhibitory effect on LX-2 cells proliferation. Sjp40 treatment for 96 h markedly suppressed ...
‘p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities’. Molecular Cell, vol. 2(3), 305-316, Sep. 1998. Bowen, et al. ‘Emerging roles for PAX8 in ovarian cancer and endosalpingeal development’ Gynecologic ...