P2Y12 receptor 通路(Pathway) GPCR/G Protein--P2Y Receptor CAS号(CAS NO.) 150322-43-3 分子式(Formula) C20H20FNO3S 分子量(Molecular Weight) 373.44 外观(Appearance) 粉末 纯度(Purity) ≥98% 溶解性(Solubility) 溶于DMSO 结构式(Structure) ...
Selatogrel: 一种P2Y12 receptor拮抗剂药物,由Idorsia Ltd. (Idorsia Ltd.)公司最早进行研发,目前全球最高研发状态为临床3期,作用机制: P2Y12 receptor拮抗剂(嘌呤P2Y12受体拮抗剂),治疗领域: 心血管疾病,在研适应症: 急性心肌梗塞,在研机构: Idorsia Pharmaceuticals
在本研究中,团队研究人员利用集落刺激因子1受体(Colony stimulating factor-1 receptor,CSF1R)的抑制剂清除脑中小胶质细胞后,发现缺失了小胶质细胞的小鼠会提前从麻醉中苏醒(图1)。进一步结合脑电记录和翻正反射等分析方法发现,小鼠缺失小胶质细胞后,对全身麻醉剂的敏感性降低,表现为麻醉深度的降低和提前苏醒(图1)。
2.Identification of High-Affinity P2Y12 Antagonists Basedon a Phenylpyrazole Glutamic Acid Piperazine Backbone 3.Recent Advances in the Development of P2Y12 Receptor Antagonists asAntiplatelet Agents 4.Pharmacogenomicsof clopidogrel: evidence and perspectives 5.Identification of the human cytochrome P450 enzym...
COX x P2Y12 receptor 作用机制 COX抑制剂[+1] 在研机构 Torrent Pharmaceuticals Ltd. 原研机构 Torrent Pharmaceuticals Ltd. 在研适应症 急性冠状动脉综合征 非在研适应症- 最高研发阶段批准上市 首次获批国家/地区 印度 首次获批日期2016-01-01 1,670 ...
一、ADP受体(ADP receptor) 在血小板表面,ADP可以与2种嘌呤受体(Purinergic receptor)相互作用,分别称为P2Y1受体和P2Y12受体。这些嘌呤受体,属于7次跨膜(7TM)受体家族,属于G蛋白偶联受体,统称为ADP受体。 此外,血小板上,还有一种P2X1...
P2Y受体 | P2Y12 Receptor 英文名称: 总访问: 26 国产/进口: 进口 半年访问: 3 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 电询 最后更新: 2024-11-4 货号: HY-I1422 CAS 号: 参考报价: 电询 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:...
P. (2011). The P2Y(12) receptor as a target of antithrombotic drugs. Purinergic Signal 7, 325-332. [4] Kamran, H., Jneid, H., Kayani, W. T., Virani, S. S., Levine, G. N., Nambi, V., et al. (202...
Platelets express a wide range of receptors and proteins that play essential roles in thrombus formation. Among these, the P2Y12receptor, a member of the G protein-coupled receptor family, has attracted a significant amount of attention. Stimulation of the P2Y12receptor by ADP results in activatio...
Platelets express a wide range of receptors and proteins that play essential roles in thrombus formation. Among these, the P2Y12receptor, a member of the G protein-coupled receptor family, has attracted a significant amount of attention. Stimulation of the P2Y12receptor by ADP results in activatio...