该ABCB1(P糖蛋白)产品的应用类型详情查看产品说明书。 免疫原 Human recombinant protein fragment corresponding to amino acids 995-1280 of human ABCB1 (NP_000918) produced in SF9 cell. 来源宿主 mouse 反应性 该Cdx1产品的反应性详情查看产品说明书。
Thus, we showed here for the first time that ABCB1 is involved in neo-absorbed vitamin D efflux by the enterocytes and that it also contributes to vitamin D transintestinal excretion and likely impacts vitamin D status.-Margier, M., Collet, X., le May, C., Desmarchelier, C., Andr...
蛋白别名:ATP-binding cassette sub-family B member 1; ATP-binding cassette, sub-family B (MDR/TAP), member 1; ATP-dependent translocase ABCB1; CD243; colchicin sensitivity; doxorubicin resistance; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1 ...
Purified anti-CD243 (ABCB1, P-glycoprotein 1) Anti产品类别:抗体 产品编号:907001 产品应用 :907001规格 价格库存 1mL ￥ 7248 1 立即订购 订购热线:021-34661276 收藏此商品 我要询价 上海细胞库人源细胞系 稳转细胞系 基因敲除株 基因点突变细胞株 大鼠细胞系 小鼠细胞系 其他细胞系...
P-糖蛋白的基因由MDR1、ABCB1或ABC1命名,编码的蛋白质包含1280个氨基酸残基。其经翻译和修饰后被转运到细胞膜上,形成一个由12个跨膜螺旋结构组成的分子,可分为两个对称的半通透通道结构。蛋白质的N端朝胞质,C端朝细胞外。 该蛋白质主要由两个重要功能域组成:核苷酸结合结构域(nucleotide-binding domains, NBDs...
The ABCB1 gene was cloned from non-polarized tumor cells where it confers multidrug resistance. P-gp is also expressed on organ barriers where it plays a protective role and affects the ADME of drugs. P-gp causes clinically significant DDIs, particularly for those drugs with a narrow ...
查看其他33个P-Glycoprotein (ABCB1)抗体 货号MA1-26528 Price (CNY) 6,652.00 250 µL 下单后预计有货时间 21-Apr-2025 查看价格 批量或定制请求 Application Created with Sketch. 图:1/19 P-Glycoprotein Antibody (MA1-26528) in WB Western blot was performed using Anti-P-Glycoprotein Monoclonal Antib...
www.nature.com/scientificreports OPEN RSK1 protects P-glycoprotein/ ABCB1 against ubiquitin– proteasomal degradation by received: 13 June 2016 downregulating the ubiquitin-accepted:11October2016 conjugating enzyme E2 R1Published:27October2016 Kazuhiro Katayama, Chiaki Fujiwara, Kohji Noguchi &...
P-Glycoprotein/ABCB1 is a member of the ABC transporter family, and facilitates the efflux of various anticancer drugs, including anthracyclines, vinca alkaloids, epipodophyllotoxins, taxanes, and kinase inhibitors, from cells. P-Glycoprotein is also expressed in normal tissues and cells, including ...
FBXO15 regulates P-glycopro- tein/ABCB1 expression through the ubiquitin-proteasome pathway in cancer cells. Cancer Sci 104: 694 -702, 2013.Katayama K, Noguchi K, Sugimoto Y. FBXO15 regulates P-glycoprotein/ABCB1 expression through the ubiquitin–proteasome pathway in cancer cells. Cancer Sci...