Blank M; Baraam L; Eisenstein M;.beta2-Glycoprotein- I based peptide regulate endothelial cells tissue-factor expres sion via negative regulation of pGSK3beta expression and re- duces experimental-antiphospholipid-syndrome.J Autoimmun.2011.8-17...
beta(2)-Glycoprotein I (beta(2)-GPI) is a protein that circulates in blood at high concentrations. The function of beta(2)-GPI has long been an enigma. More than 20 years ago, it was discovered that beta(2)-GPI is the major antigen for the circulating antibodies in the antiphospholipi...
anticardiolipin antibodies, anti-beta-2-glycoprotein I antibodies, antiphospholipid syndrome, autoimmune diseasesThe anticardiolipin (aCL) antibody test was first established in 1983, using cardiolipin (negatively charged phospholipid) as an antigen in a solid-phase immunoassy. It was first applied to ...
To characterize the reactivity pattern of Abs directed to beta2-glycoprotein I (anti-beta2GPI) in patients with anti-phospholipid syndrome, we have purified anti-beta2GPI Abs by affinity chromatography using the IgG fractions from sera o... A Tincani - 《Journal of Immunology》 被引量: 268...
Beta 2-glycoprotein I (β2GPI/Apolipoprotein H) is an abundant plasma protein that is produced by the liver7. It is composed of five domains (DI-V), and has a molecular weight of approximately 50 kDa7. Domains I to IV each have two disulfide bridges, whereas domain V has three...
While anti-PL Abs found in the sera of patients with infectious diseases bind directly to CL, binding of anti-PL Abs to CL circulating in the sera of patients with autoimmune diseases is mediated by glycoprotein 1 (). The purpose of this study is to investigate the effect of <on the ...
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A protein (911aa) of the human erythrocyte membrane, identified as the major anion transport/exchange protein. Analogous proteins exist in other erythrocytes. A dimeric transmembrane glycoprotein, with binding sites for many cytoplasmic proteins, includingankyrin, on its cytoplasmic domain. ...
A dimeric transmembrane glycoprotein, with binding sites for many cytoplasmic proteins, including ankyrin, on its cytoplasmic domain. banding patterns Chromosomes stained with certain dyes, commonly quinacrine (Q banding) or Giemsa (G banding), show a pattern of transverse bands of light and heavy ...
The filoviruses, including Marburg and Ebola, express a single glycoprotein on their surface, termed GP, which is responsible for attachment and entry of t... Takao,Hashiguchi,L Marnie,... - 《Cell》 被引量: 99发表: 2015年 Structural basis for antibody recognition in the receptor-binding ...