1) P-cadherin gene P-cadherin基因 2) E-cadherin gene E-cadherin基因 1. PURPOSE: To construct ACC-M cell line of RNA interference-mediated knockdown of DNMT1, and to explore the effects onE-cadherin geneexpression in this cell line. ...
gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with ...
别名 cadherin 3 , CDHP , HJMD , PCAD 细胞定位 Cell membrane 功能与背景 This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly...
CDH3/P-Cadherin regulates migration of HuCCT1 cholangiocarcinoma cells. PMID: 21189991 CDH3 gene related hypotrichosis and juvenile macular dystrophy - A case with a novel mutation. PMID: 29260097 New CDH3 mutation in the first Spanish case of hypotrichosis with juvenile macular dystrophy, a case ...
CDH3 geneP‐cadherinCancer stem cellsBiomarkerBasal‐like breast cancerAlthough the luminal progenitor cell of the normal mammary gland hierarchy has been proposed as the cell-of-origin for basal-like breast cancers, finding the cancer stem cell (CSC) phenotype for this malignancy has proven a ...
1.Splice variants: Alternative splicing may create different sized proteins from the same gene. 2. Relative charge: The composition of amino acids may affects the charge of the protein. 3. Post-translational modification: Phosphorylation, glycosylation, methylation etc. 4. Post-translation cleavage: ...
Gene P-Cadherin Alias P-Cadherin(Cadherin, Placental), Cadherin-3, Placental cadherin, CAD3, CDH3, CDHP, HJMD, PCAD, cadherin 3, P-cadherin(placental), cadherin 3, type 1, P-cadherin(placental), HJMD Sensitivity 37.5pg/ml Range 62.5-4000pg/ml Detection Method Sandwich ELISA, Double An...
CDH3 (redirected fromP-cadherin) CDH3 A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells. CDH3 is also a retired HUGO symbol for what is ...
背景资料 Cadherins,such as CDH3,are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion.Cadherin-3 is a protein that in humans is encoded by the CDH3 gene.This gene is a classical cadherin from the cadherin superfamily.The encoded protein is a calcium-dependent ce...
基因序列:NCBI_Gene:1001 蛋白序列:UniProtKB:P22223 人Human CDH3靶点分子功能(预测) Predicted to enable cadherin binding activity and calcium ion binding activity. Involved in several processes, including negative regulation of timing of catagen; positive regulation of signal transduction; and regulation ...