ScPMA1, a gene that encodes a P-type ATPase responsible for maintaining hydrogen-ion homeostasis across the plasma membrane in yeast11, was the only essential gene among those identified. It is also a homolog of a KAE609 resistance-conferring gene in P. falciparum, PfATP4 (Fig. 1b). ...
Global transcriptional analysis of loblolly pine (Pinus taeda L.) is challenging due to limited molecular tools. PtGen2, a 26,496 feature cDNA microarray, was fabricated and used to assess drought-induced gene expression in loblolly pine propagule roots.
Alternative models involve energy-dependent export of chloroquine by a transporter of the ABC cassette or mdr type (34, 38). Our searches of the cg2 ORF have not identified homology with an ion channel or transporter favoring one or another of these different models. Immunoelectron microscopy of...
This promoter shows high quasi-constitutive activity [60] at the start of the stationary phase, and is relatively independent of medium composition and pH [61]. Application of the hp4d growth dependent promoter lessens the metabolic burden of YlALK5 overexpression during the growth phase. The ...