human WB,IF Mol Cell An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress. Authors - Julian Nüchel View Article human IF Nat Commun AmotL2 disrupts apical-basal cell polarity and promotes tumour invasion. Authors - Mahdi Mojallal View...
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation. Authors - Katharina Fitzian KD Validated View Article human WB Elife Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes. Authors - Sa...
Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. 引用文献 Citation No Data All 0 page Home Previous Next Last 用户反馈 User feedback 用户名: 评论内容: 评论时间: 回复内容: 回复时间: 上一页 下...
Western blot(WB) was performed to study the protein level of SASH3 and the NF-kB and mTORC1 pathways in patients. RESULTS. P1 was diagnosed with Crohn's disease according the images of endoscopy and biopsies (Figure A). WES and sanger sequencing identical a variant at exon1 in SASH3 (...
WB检测肌动蛋白结合蛋白(actin binding proteins,ABPs)Arp3和Eps8,mTORC1及mTORC2信号通路相关指标(Rictor,p-rps6,rps6,Akt,p-Akt,MMP9)的表达改变.Sertoli... 沈炼桔,魏跃新,吴雨昊,... - 中国毒理学会全国毒理学大会 被引量: 0发表: 2023年 加载更多来源...
Akt通过在“ser-939”和“thr-1462”处磷酸化tsc2来介导胰岛素刺激的蛋白质合成,从而激活mtorc1信号,并导致4e-bp1的磷酸化和rps6kb1的激活。Akt参与Foxo因子(转录因子叉头家族)成员的磷酸化,导致14-3-3蛋白结合和细胞质定位。特别地,foxo1在“thr-24”、“ser-256”和“ser-319”被磷酸化。FoxO3和FoxO4在...
鸟苷酸释放因子p532蛋白抗体HERC1背景: 作为调控AKT mTOR信号通路的关键调节剂,调控成年神经发生过程中新生神经元整合的过程,包括正确的神经元定位、树突发育和突触形成。增强磷酸肌醇3-激酶(PI3K)依赖的磷酸化和激酶活性的Akt1/PKB,但不具有激酶活性本身。AKT1/PKB的磷酸化诱导下游效应物GSK3和FXO1/FKHR的磷酸化,并...
Akt通过在“ser-939”和“thr-1462”处磷酸化tsc2来介导胰岛素刺激的蛋白质合成,从而激活mtorc1信号,并导致4e-bp1的磷酸化和rps6kb1的激活。Akt参与Foxo因子(转录因子叉头家族)成员的磷酸化,导致14-3-3蛋白结合和细胞质定位。特别地,foxo1在“thr-24”、“ser-256”和“ser-319”被磷酸化。FoxO3和FoxO4在...
Knockdown of p27 by siRNAs was sufficient to mimic the effects of miR-221 overexpression on mTOR activation and autophagy inhibition, whereas overexpression of p27 rescued miR-221-induced autophagic flux impairment. Inhibition of CDK2 restored the impaired autophagic flux and rescued the cardiac ...
#动态#人雷帕霉素靶蛋白(mTOR)elisa定量检测试剂盒优势 产品详情 公司简介 公司评价 手机查看 手机查看 一键电话致商家 抗体名: 着丝粒蛋白P抗体 浓度: 1mg/1ml % 靶点: 详见说明书 宿主: 详见说明书 用途: 公司产品仅用于科研 应用范围: WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P...