Synonyms H2A.X; H2A/X; H2AX Category Epigenetics Background Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and huma...
Histone H2AX is a member of the Histone H2A family, which is involved innucleosomal organization of chromatin. The H2AX gene is located in closeproximity to the Porphobilinogen deaminase (PBG-D) gene in both mouseand human, and maps to chromosome 9 and 11q23, respectively. H2AX dif- fers...
SynonymsH2A.X; H2A/X; H2AX CategoryEpigenetics BackgroundHistone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and...
H2Ax Antibody-Anti-phospho-Histone H2AX (pSer139) antibody produced in rabbit H2Ax Antibody Anti-H2AXS139p 抗 磷酸化组蛋白 H2AX (pSer139) 兔抗 抗H2AXS139p 产品介绍: 产品说明 一般描述 H2AX占人类细胞中总H2A补体的2-25%,而在发芽酵母中,它实际上构成了所有H2A分子。它具有N末端和C末端区域,以及中心...
综述·讲座 组蛋白H2AX磷酸化与肿瘤放疗敏感性关系的研究进展曹明丽, 陈可欣天津医科大学附属肿瘤医院流行病室,天津300060RelationshipbetweenphosphorylationofhistoneH2AXandtumorradiosensitivity犆犃犗犕犻狀犵 犾犻,犆犎犈犖犓犲 狓犻狀犇犲狆犪狉狋犿犲狀狋狅犳犈狆犻犱犲犿犻狅犾狅犵狔,犜犻犪狀犼犻狀犆犪狀...
如组蛋白H3和组蛋白乙酰化酶(Histoneacetyltransferase,HAT)突变体HAT1通过Asf1p依赖的染色质重构影响DNA双链断裂(Double-strandbreak,DSB)的修复[1];组蛋白H4的乙酰化也影响了细胞DSB的修复活性[2];组蛋白H2A除参与了DNA修复,还参与了细胞减数分裂和细胞凋亡等过程[3]。组蛋白H2A家族包括H2A1、H2A2、H2AZ和H2AX...
组蛋白H2AX抗体,英文名称:Anti-Histone H2A.x,保存条件:保存在4℃(短期)或-20℃(长期),形态:Liquid,亚型:IgG等,应用范围:ELISA,WB,IHC,IP,FC,IF等,规格:100ul///200ul,宿主:Rabbit or Mouse等,适用物种:Human,Mouse,Rat等 胞质分裂调控蛋白1抗体,英文名称:Anti-PRC1,保存条件:保存在4℃(短期)或-20℃...
英文名称: H2AXS139P, Histone H2A.X (phospho S139) 品牌: Sigma-Aldrich 货号: 05-636-25UG 是否进口: 是 组蛋白H2A是参与真核细胞染色质结构的5种主要组蛋白之一。H2A具有一个主要的球状结构域和一个长N末端的尾巴,其与核糖体核小体′串珠′结构体的结构有关。 1、产品质量问题,在产品售出7日内提...
H2A组蛋白家族成员X(H2AFX)重组蛋白 Recombinant H2A Histone Family, Member X (H2AFX)H2AX [ PROPERTIES ]Source: Prokaryotic expressionHost: E.coliResiduess: Ser2~Tyr143Tags: N-terminal His and GST TagTissue Specificity: Nucleus, ChromosomePurity: > 95%Traits: Freeze-dried powder...
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks Nat Cell Biol, 5 (2003), pp. 675-679 View in ScopusGoogle Scholar Coppe et al., 2010 J.P. Coppe, P.Y. Desprez, A. Krtolica, et al. The senescence-associated secretory phenotype: the dark side of tumo...