HEPATIC STEATOSISBackground and aimsThe accumulation of misfolded proteins, encoded by genetic variants of functional genes leads to Endoplasmic Reticulum (ER) stress, which is a critical consequence in human disorders such as familial hypercholesterolemia, cardiovascular and hepatic diseases. In addition ...
3A). The reduced tumorigenicity was associated with a significant reduction in hepatic steatosis, hepatocyte ballooning, hepatocellular lipid accumulation, and hepatic inflammation (Fig. 3d–f and Supplementary Fig. 3B). Consistently, glucose sensitivity measured by the intraperitoneal glucose tolerance test...