A NEW CONCEPT FOR ENERGY COUPLING IN OXIDATIVE PHOSPHORYLATION BASED ON A MOLECULAR EXPLANATION OF THE OXYGEN EXCHANGE REACTIONSP. D. BoyerR. L. CrossW. MomsenPortland Press
Answer to: Explain the three metabolic processes of cellular respiration: glycolysis, tricarboxylic acid cycle (TAC) and oxidative phosphorylation...
Regulation of mitochondrial oxidative phosphorylation through cell signaling Biochim. Biophys. Acta, 1773 (2007), pp. 1701-1720 View PDFView articleView in ScopusGoogle Scholar Kato, 2006 T. Kato The role of mitochondrial dysfunction in bipolar disorder Drug News Perspect., 19 (2006), pp. 597-...
Sizemore N, Leung S, Stark GR (1999) Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit. Mol Cell Biol 19:4798–805 Article CAS PubMed PubMed Central Google Scholar Sizemore N, Lerner N, Dombrowsk...
4.7. Development and expansion of the WOMED model: the pathway to an acquired alteration of mitochondrial function affecting Complex V of oxidative phosphorylation 4.7.1. Ankle sprain grade I as the trigger We postulate that the chain of events involved in the development of thyroid disease begins...
The role of stress-activated kinases JNK and IKK in regulating FOXO was already included in this model; here we have extended this to include their regulation of IS through phosphorylation of IRS. ROS is included in the model and leads to activation of SAPKs while also having a direct ...
In various rat tissues including testis, liver, and lung, monensin was demonstrated to inter- fere with the proper shuttling of protons across the IMM leading to a loss in mitochondrial membrane potential as well as interruption of the electron transport chain, oxidative phosphorylation, and ATP ...
similar to those of Qiu et al. [66]. Similarly, in previous study, RES treatment increased the epithelial expression and phosphorylation of occludin and ZO-1 in a concentration-dependent manner. Moreover, RES which protected Caco-2 cells from H2O2-induced oxidative damage clearly reduced malondial...
Functional assays showed that cells with heteroplasmic mutant mtDNA were able to recover respiratory capacity and oxidative phosphorylation enzymes activity after transfection with the mitoTALEN. To improve the design in the context of the low complexity of mtDNA, we designed shorter versions of the ...
Most cellular ROS arise due to “leakage” of electrons from the mitochondrial respiratory chain resulting in incomplete reduction of molecular oxygen during oxidative phosphorylation to produce hydrogen peroxide (H2O2) and the superoxide radical anion (O2−, Fig. 1). Whilst cytochrome C (the ...