Oxidative phosphorylation (OXPHOS) is a multi-enzyme process located in the inner mitochondrial membrane (IMM) by which electrons from reduced metabolites are transferred to the ultimate electron acceptor oxygen, which is reduced to water. From: Journal of Molecular Biology, 2018 ...
2003,Encyclopedia of Food Sciences and Nutrition (Second Edition) S.Rubinstein-Litwak Explore book Oxidative Phosphorylation Oxidative phosphorylationis also known as theelectron transportchain. It includes the reactions that result in the synthesis of ATP from ADP + Pi. Heat can also be generated whe...
Antioxidants had a growing interest owing to their protective roles in food and pharmaceutical products against oxidative deterioration and in the body and against oxidative stress-mediated pathological processes. Screening of antioxidant properties of plants and plant-derived compounds requires appropriate met...
Intracellular DNA-sensing pathway cGAS-STING, inflammasomes and pyroptosis act as critical natural immune signaling axes for microbial infection, chronic inflammation, cancer progression and organ degeneration, but the mechanism and regulation of the cro
Model Cell line/species Dose Effect Mechanism Ref LPS-induced RAW264.7 0.01 to 1 μmol/L Suppression of NO production Inhibition of iNOS protein expression; [30] inflammation suppression of IκBα phosphorylation and p65 nuclear translocation 0.01 to 1 μmol/L NR Decrease of TNF-α production ...
with MVEs. The KRAS–MEK signaling pathway may control the loading of specific exosomal miRNAs through Ago2 phosphorylation.76Deficiency of AGO2 has been observed to restrict the enrichment of some preferentially exported miRNAs, such as miR-451, miR-150, and miR-142-3p, in exosomes derived fr...
Bidens pilosa L. is an edible herb and has been traditionally used for a wide range of ailments in many countries. The aim of this review is to present com
Reactionsofthepyruvatedehydrogenasecomplex Thefirststepintheoxidationofpyruvateisanoxidativedecarboxylationreaction.Thisreactioniscarriedoutbyaverylargeenzymecomplex,thepyruvatedehydrogenasecomplex,whichislocatedinthemitochondrialmatrix.Thereactioncatalyzedbythepyruvatedehydrogenasecomplexisirreversible,andistightlyregulated. ...
It is the main metabolic pathway in activated neutrophils, rendering them relatively insensitive to inhibitors of oxidative phosphorylation. Congenital deficiency of the first enzyme in the shunt produces a sensitivity to infection similar to that seen in chronic granulomatous disease. pentoses Sugars (...
Possible mechanisms behind this Cd effect on the thyroid gland can be oxidative stress (i.e., oxidative phosphorylation disorders in mitochondria of follicular cells) as suggested by many authors [46,62,66]. Further investigations of mechanisms of direct Cd thyroid toxicity were conducted in vitro...