Ovarian Carcinoma (with comments on Fallopian Tube Carcinoma): this chapter outlines the incidence, risk factors, clinical presentation, investigations, treatments and prognosis of cancer at this anatomical site. These features are correlated with the core data that are required to make corresponding ...
While, of carcinomas with a homologous recombination mutation in 14 key non-BRCA HRR genes, 37 (88.1%) were Pt-sensitive (p = 0.062). Although the difference was not but not statistically significant, a trend of longer PFS was observed in patients with a germline or somatic HRR ...
the Notch 1 extracellular domain (Notch 1-EC, 120 kDa) and of the downstream transcription factor HES1 (32 kDa) in 28 of the 32 ovarian tumours (16 ovarian carcinomas, three borderline tumours, nine ovarian adenomas), in three human ovarian cancer cell lines and one ovarian ...
KGN cells, established by long-term culture of human ovarian granulosa cell carcinoma, have steroidogenic activities and express functional FSH receptors. Thus, this cell line is considered a very useful model to explore the physiological regulation of human granulosa cells51,52. We found that Ab4...
Clear cell carcinomaOvarian carcinomaE-cadherinbeta-cateninBeta-cateninGlypican-3E-CADHERIN EXPRESSIONNUCLEAR E-CADHERINGLYPICAN-3 EXPRESSIONBETA-CATENINTumor budding, largely considered a manifestation of epithelial-mesenchymal transition (EMT) is an established prognostic marker for several cancers. In a ...
There are now many different groups following the recognition of serous tumors with microinvasion, non-invasive and invasive peritoneal implants and a micropapillary pattern, and of mucinous tumors with microinvasion, intraepithelial carcinoma and pseudomyxoma peritoneal implants, in addition to further ...
There are now many different groups following the recognition of serous tumors with microinvasion, non-invasive and invasive peritoneal implants and a micropapillary pattern, and of mucinous tumors with microinvasion, intraepithelial carcinoma and pseudomyxoma peritoneal implants, in addition to further ...
There are now many different groups following the recognition of serous tumors with microinvasion, non‐invasive and invasive peritoneal implants and a micropapillary pattern, and of mucinous tumors with microinvasion, intraepithelial carcinoma and pseudomyxoma peritoneal implants, in addition to further ...
Inter-tumor heterogeneity is a result of genomic, transcriptional, translational, and post-translational molecular features. To investigate the roles of protein glycosylation in the heterogeneity of high-grade serous ovarian carcinoma (HGSC), we perform
It is an inconspicuous tissue with no known major function, but it is of great importance in gynecologic pathology because it is the source of the most common and most lethal form of human ovarian malignancies—the epithelial ovarian carcinomas.NELLY AUERSPERG...