CancerD-loopmitochondriaoutcomeovarianObjective: The single nucleotide polymorphisms (SNPs) in the displacement loop (D-loop) of mitochondrial DNA (mtDNA) is found in many types of cancers. A lot of reports show the SNPs of D-loop may be related to cancers prognosis. This study investigated ...
The risk and prognosis of ovarian cancer have not been well established in women with endometriosis. Thus, we investigated the impact of endometriosis on the risk and prognosis for ovarian cancer, and evaluated clinicopathologic characteristics of endometriosis-associated ovarian cancer (EAOC) in compari...
Ovarian cancer is difficult to diagnose because symptoms often do not occur until late in the disease. Symptoms do not occur until the tumor has grown large enough to apply pressure to other organs in the abdomen, or until the cancer has spread to remote organs. The symptoms are nonspecific,...
it is believed that ovarian cancer affects mainly nulliparous women (those, who had never given birth). Also, there is an opinion that ovarian cancer may be prevented by taking oral contraceptives. Without a doubt, ovarian cancer (as well as other types of cancer) may be inherited from...
The majority of Mater patients (72%) had either stage I or stage II ovarian cancer which is at variance with other studies and may reflect an under-staging at initial laparotomy. Their survival rates were better than those of the STR, probably because they had presented earlier and had a ...
In this paper, we analyze ovarian cancer cases from six hospitals in China, screen the prognostic factors and predict the survival rate. The data has the f
Epithelial ovarian cancer (EOC) is a deadly disease with limited diagnostic biomarkers and therapeutic targets. Here we conduct a comprehensive proteomic profiling of ovarian tissue and plasma samples from 813 patients with different histotypes and thera
YAP Promotes Ovarian Cancer Cell Tumorigenesis and Is Indicative of a Poor Prognosis for Ovarian Cancer Patients YAP is a key component of the Hippo signaling pathway and plays a critical role in the development and progression of multiple cancer types, including ovarian cancer. However, the effects...
Ovarian cancer (OC) is the second most common gynecological malignancy and the fifth leading cause of death due to cancer in women in the United States. These statistics reflect mainly the late-stage diagnosis and poor prognosis of OC1,2,3. Ovarian cancer consists of two major types: Type ...
The presence of advanced ovarian cancer is often suspected on clinical grounds, but it can be confirmed only pathologically by removal of the ovaries or, when the disease is advanced, by sampling tissue or ascitic fluid. Screening The US Preventive Services Task Force (USPSTF) recommends against...