Most of the gene candidates for the control of developmental programmes that underlie brain morphogenesis in vertebrates are the orthologues of Drosophila genes coding for signalling molecules or transcription factors. Among these, the orthodenticle group, including the Drosophila orthodenticle (otd) and ...
Here I report the cross-phylum regulatory potential of the ascidian Otx gene in the development of the Drosophila brain and the head vertex structures. The ascidian Otx gene rescued the embryonic brain defect of Drosophila caused by null mutation of the orthodenticle (otd) gene and enhanced ...
Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy and slow photoreceptor degeneration. PLoS One 5, e11673.F. Beby, M. Housset, N. Fossat, G. C. Le, F. Flamant, P. Godement, and T. Lamonerie, Otx2 gene deletion in adult mouse retina induces rapid RPE dystrophy ...
The orthodenticle homeobox 2, encoded by OTX2 gene, is a key transcription factor in developmental processes. In particular, it is required for the early specification of the brain and the embryonic development of sensory organs, including the, pineal gland, pituitary gland, inner part of the ...
Home > Section > Chapter Boncinelli, E.; Gulisano, M.; Broccoli, V. Journal of Neurobiology 24(10): 1356-1366 1993 ISSN/ISBN:0022-3034 7901323 10.1002/neu.480241008 031228878 Article emailed within 0-6 h Buy Now for$19.90 Payments are secure & encrypted ...
作为杆菌,例如使用枯草芽孢杆菌MI114(Gene,vol.24,255(1983)),和207-21(Journal of Biochemistry,vol.95,87(1984))。作为酵母,例如使用酿酒酵母(Saccharomyces cerevisiae)AH22,AH22R-,NA87-11A,DKD-5D,20B-12,粟酒裂殖酵母(Schizosaccharomyces pombe)NCYC1913,NCYC2036和巴斯德毕赤氏酵母(Pichia pastoris)。
Pseudogenes of this gene are known to exist on chromosomes two and nine. 关键字: Anti-OTX2 Polyclonal Antibody;抗体 公司简介 北京索莱宝科技有限公司是一家集研发、生产、销售、服务于一体的高科技生物企业。技术推广;技术转让;技术咨询;技术服务;生物试剂技术开发;销售生物试剂盒、实验室专用化学试剂、实验...
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development.Tissue specificity...
0.00% Treatment with OTX-2002 led to controlled downregulation of MYC gene expression and resulted in significant inhibition of tumor growth as a monotherapy and in combination with standard of care agents in preclinical models of HCC Proof-of-concept data for OTX-2002 support potential of epigenomi...
This in turn prevents gene transcription. OTX015 has been shown to inhibit proliferation of cells in haematological malignancies.OTX015 is a potent inhibitor of the BET bromodomain proteins 2, 3, and 4 (BRD2/3/4). 基本信息 经验(实验)分子式 C25H22ClN5O2S 分子量 491.99 MDL编号 MFCD26960949...