An additional section summarizes the hypnotic agents currently available for the treatment of short-term and long-term insomnia. Drug dosing tables congruent with the narrative sections have been inserted. Each section is organized in a similar fashion with subsections for indications, efficacy, dosing...
High A4GS is unique for AIH and independent of remission status, which offers possibilities for development of new diagnostic markers, potentially reducing the need for liver biopsy. Secondly, it can also offer a new perspective on pathophysiology of AIH. Glycosidic changes related to disease ...
Our follow-up time was eight to 18 weeks postoperatively. In order to truly evaluate a long-term effect of surgical excision of endometriotic lesions, further data with a longer follow-up period should follow. Conclusions This study demonstrates that the surgical removal of endometriotic lesions ...
The pathways for each drug were obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG) database (https://www.kegg.jp/kegg/). Definition of AEs and drug names The target AE in this study was NMS (preferred term (PT) code:10,029,282), which was extracted from the data table...
Silbert PL, Edis RH, Stewart-Wynne EG et al (1991) Benign vascular sexual headache and exertional headache: interrelationships and long term prognosis. J Neurol Neurosurg Psychiatry 54:417–421 Article PubMed Central CAS PubMed Google Scholar Sjaastad O, Bakketeig LS (2002) Exertional headach...
In addition to the direct nephrotoxicity of some antiretrovirals, anti-HIV treatment also includes a toxicity which pathophysiology is not completely elucidated. This nephrotoxicity is the consequence of organ accelerated ageing and of an increased vascular risk. Kidney vascularization (from renal ...
Current approaches for the treatment of homozygous FH include statin-based lipid-lowering therapies and LDL apheresis. Mipomersen is a second-generation antisense oligonucleotide (ASO) targeted to human apolipoprotein B (apoB)-100. This review provides an overview of the pathophysiology and current ...
These studies provide proof of principle for IGF-1R kinase inhibition as a therapeutic strategy for a broad spectrum of malignancies, and elucidate previously unidentified aspects of the pathophysiology of IGF-1R and its downstream molecular mediators. These results also provide the rationale for the ...
Secondary Neoplasia (SN) after HCT belong to the most feared long-term complications. They include any malignant disorder occurring after HCT. There are three types of SN: therapy-related myeloid neoplasms, occurring mainly after auto-HCT; donor-derived
Role of long non-coding RNAs in the pathophysiology of Alzheimer’s disease and other dementias Abstract Dementia is the term used to describe a group of cognitive disorders characterized by a decline in memory, thinking, and reasoning abilities that interfere with daily life activities. Examples ...