Verrotti A, Greco R, Morgese G, Chiarelli F. Carnitine deficiency and hyperammonemia in children receiving valproic acid with and without other anticonvulsant drugs. Int J Clin Lab Res 1999;29:36-40.Verrotti A, Greco R, Morgesc G, Chiarelli F. Carnitine deficiency and hyperammonemia in ...
Total blood carnitine was lowered with unesterified carnitine being half of the lowest control value. A diagnosis of mild MCAD deficiency (MCADD) was based on rates of 1-14C-octanoate and 9, 10-3H-myristate oxidation and of octanoyl-CoA dehydrogenase being reduced to 25% of control values. ...
most respiratory chain defects are not.When mitochondrial ATP synthesis has been compromised by a mitochondrial defect, secondary lesions may be generated by changes in mitochondrial protein synthesis, activated proteases and phospholipases, increased matrix CoA and resulting carnitine deficiency, decrease ...
Primary and secondary coenzyme Q10 deficiency: The role of therapeutic supplementation. Nutr. Rev. 2013, 71, 180–188. [Google Scholar] [CrossRef] Garcia-Corzo, L.; Luna-Sanchez, M.; Doerrier, C.; Ortiz, F.; Escames, G.; Acuna-Castroviejo, D.; Lopez, L.C. Ubiquinol-10 ameliorates...
Fatty acid metabolism disorders diagnoses included carnitine deficiency, Reye’s syndrome, carnitine palmitoyltranferase 2 (CPT2) deficiency, medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, and very-long-chain acyl-CoA dehydrogenase (VLCAD) deficiency. Viral infections included rotavirus, hand-...
It provides a secondary active transport when glucose uptake by cancer cells is insufficient but requires energy in the form of adenosine triphosphate (ATP). For example, the E6 protein of HR HPV18 regulates the SGLT1 transporter [177]. EGFR is often strongly expressed and activated in cancer ...
As secondary endpoints, the following were assessed: • Time elapsed from admission to the sub-intensive care unit until functional goals were achieved; • Characteristics of admission, including duration of ventilation; • Length of stay in the sub-intensive care unit; • Duration of ...