Carnitine deficiency can be misdiagnosed as a progression of systemic muscle atrophy. Clinicians should be aware of this disorder and should consider periodically measuring carnitine levels, regardless of the patient's serum ammonium levels.Naohi Isse...
Carnitine deficiency can be misdiagnosed as a progression of systemic muscle atrophy. Clinicians should be aware of this disorder and should consider periodically measuring carnitine levels, regardless of the patient's serum ammonium levels. 展开 关键词: Amyotrophic lateral sclerosis Carnitine deficiency ...
Human carnitine palmitoyl transferase (CTP) deficiency results in two different clinical variants, one with "hepatic" and one with "muscular" symptoms. We studied CPT activity and long-chain fatty acid oxidation in fibroblast cell lines ... F Demaugre,JP Bonnefont,G Mitchell,... - 《Pediatric...
If the deficiency is severe and persists, especially in malnourished infants and children, a condition known as xerophthalmia may develop. In xerophthalmia, the eyes are sensitive to light, the secretion of lubricating tears is stopped, and the eyelids become swollen and sticky with pus. The mucou...
Since both leptin [16] and acetyl-L-carnitine [52] appear to be decreased in MDD, a negative association with insomnia would support a contribution of insomnia to metabolic changes in MDD. However, the present study does not confirm such a relationship in MDD. To summarize, the current ...
In 7 children with single episodes of Reye's syndrome serum (n=4), muscle (n=3) and liver (n=1) free carnitine levels were normal except for one slightly low serem level. Systemic carnitine deficiency may mimic "Reye's syndrome"; the episodes, some initiated by fasting, may be prevent...
Carnitine-acylcarnitine translocase deficiency: Identification of a novel molecular defect in a Bedouin patient Kazanovitz A, Moses SW, Hershkovitz E (2004) Carnitine-acylcarnitine translocase deficiency: identification of a novel molecular defect in a Bedouin patient... D Galron,OS Birk,A Kazanovitz...
Systemic and organ specific carnitine (CAR) deficiency: A possible cause of cardiomyopathy (CM) in man and syrian hamsters: V. Regitz, M.E. Tripp, D. Paulson and A.L. Shug. Department of Pediatrics, University Hospital and V.A. Hospital, Madison, Wisconsin, USA Available online 28 January...
The decrease in carni- tine levels may prevent β-oxidation of lipids in the OP group, which in turn contributed to the observed energy insufficiency and liver damage. However, after administration of C sinensis, the levels of L-carnitine were upregulated towards normal lev- els, which may ...
The mechanism of action is based on the Bmonoamine hypothesis^, which pro- poses that the main cause of depression is a deficiency of the neurotransmitters noradrenaline (NA) and serotonin (5-HT, 5- hydroxytryptamine) in the brain. However, different classes present different mechanisms of ...