Thalidomide (alpha-phthalimidoglutarimide), sold in Europe and Canada since 1959 under many trade names (Distaval, Contergan, Kevadon, etc.), and originally promoted by some companies as a "new, non-barbiturate" sedative with "no known toxicity", has caused gross malformations in newborn ...
With the effects of thalidomide and rubella before us we would surely be ready to accept slighter but similar evidence with another drug or another viral disease in pregnancy.” Hill’s final word on what has come to be known as his criteria for deciding about causation: “Here then are ...