Use of zoledronate to treat osteoblastic versus osteolytic lesions in a severe-combined-immunodeficient mouse model. Cancer Res. 2002; 62 :5564–5570.Lee YP, Schwarz EM, Davies M, Jo M, Gates J, Zhang X, Wu J, Lieberman JR. Use of zoledronate to treat osteoblastic versus osteolytic ...
There were 145 bone lesions (22.8% osteoblastic, 53.1% osteolytic, and 24.1% mixed) on CT. Osteoblastic lesions had a significantly higher value of CT HU as compared to osteolytic and mixed lesions (P < 0.01). There was no significant difference in mean ROImax and mean SUVmax ...
4,44 Osteocytes influence bone remodeling in both osteoblastic and osteolytic lesions, although little is known about their roles in osteotropic cancer bone metastasis.4 The glycoprotein sclerostin, which we identified at the gene/protein levels here, is only expressed by mature osteocytes.21 ...
Multiple mechanisms contribute to tumor cells homing to bone and the subsequent development of bone lesions. Adhesion molecules expressed on tumor cells and cellular products from tumor cells also increase bone metastasis. In osteolytic metastasis and multiple myeloma (MM), the bone remodeling process ...
(p<0.01)were significantly increased along the femur shaft.Conclusion:PCSD1 cells reproducibly induced bone loss leading to osteolytic lesions at the ends of the femur,and,in contrast,induced aberrant bone formation leading to osteoblastic lesions along the femur shaft.Therefore,the interaction of PC...
Results:We found that PC3c cells induced mixed lesions 10 weeks after intratibial injection. Invitro, PC3c conditioned medium was able to stimulate tartrate resistant acid phosphatase (TRAP)-positive osteoclasts. Osteoprotegerin (OPG) and endothelin-1 (ET1) were highly expressed by PC3c while dik...
Lee Y, Schwarz E, Davies M, Jo M, Gates J, Wu J, et al.: Differ- ences in the cytokine profiles associated with prostate cancer cell induced osteoblastic and osteolytic lesions in bone. J Orthop Res 2003; 21: 62-72Lee Y,Schwarz E,Davies M,et al.Differences in the cytokine ...
Differences in the cytokine profiles associated with prostate cancer cell induced osteoblastic and osteolytic lesions in bone. J Orthop Res 2003;21(1):62-72.Differences in the cytokine profiles associated with prostate cancer cell induced osteoblastic and osteolytic lesions in bone. Lee Y,Schwarz E...
Body JJ. Rationale for the use of bisphosphonates in osteoblastic and osteolytic bone lesions. Breast. 2003; 12 (Suppl 2):S37–S44. doi: 10.1016/S0960-9776(03)80162-5. [ Cross Ref ]Body JJ . 2003 . Rationale for the use of bisphosphonates in osteoblastic and osteolytic bone lesions ...
11C- choline PET/CT identifies osteoblastic and osteolytic lesions in patients with metastatic prostate cancer. Clin Nucl Med. 2015;40:e265-70. doi:10.1097/RLU. 0000000000000783.Ceci F,Castellucci P,Graziani T,et al.11 C-Choline PET/CT identifies osteoblastic and osteolytic lesions in patients ...