osteolineage cell 是什么细胞?骨系细胞，来自间充质干细胞，可分化为成骨细胞、软骨细胞、脂肪细胞[1]...
^Calvi LM. Osteolineage cells and regulation of the hematopoietic stem cell. Best Pract Res Clin Haematol. 2013 Sep;26(3):249-52. doi: 10.1016/j.beha.2013.10.004. Epub 2013 Oct 16. PMID: 24309526.^Tan SH, Senarath-Yapa K, Chung MT, Longaker MT, Wu JY, Nusse R. Wnts produced...
Osteolineage cell-derived extracellular vesicles (EVs) play a regulatory role in hematopoiesis and have been shown to promote the ex vivo expansion of human hematopoietic stem and progenitor cells (HSPCs). Here, we demonstrate that EVs from different human osteolineage sources do not have the same...
Osteolineage niche cells initiate hematopoietic stem cell mobilization Recent studies have implicated bone-lining osteoblasts as important regulators of hematopoietic stem cell (HSC) self-renewal and differentiation; however, ... SR Mayack,AJ Wagers - 《Blood》 被引量: 247发表: 2008年 Regulation of...
LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells Xin-Jiang Lu, Qiang Chen, Ye-Jing Rong, Guan-Jun Yang, Chang-Hong Li, Ning-Yi Xu, Chao-Hui Yu, Hui-Ying Wang, Shun Zhang, Yu-Hong Shi & Jiong Chen Natu...
AML Differentially Alters Fate and Function of Mesenchymal Stem- and Osteolineage Cells in the Leukemic Niche doi:10.1182/blood.V130.Suppl_1.1197.1197Acute Myeloid Leukemia (AML) alters the composition of the supportive bone marrow (BM) stroma, leading to a leukemia-supportive microenvironment that ...
macrophages and osteolineage cells Xin-Jiang Lu1, Qiang Chen1, Ye-Jing Rong1, Guan-Jun Yang1, Chang-Hong Li1, Ning-Yi Xu2, Chao-Hui Yu3, Hui-Ying Wang4, Shun Zhang5, Yu-Hong Shi1 & Jiong Chen1 Haematopoietic stem cells (HSCs) can differentiate into cells of all lineages in the ...
There is evidence suggesting that N-cadherin expression on osteoblast lineage cells regulates hematopoietic stem cell (HSC) function and quiescence. To test this hypothesis, we conditionally deleted N-cadherin (Cdh2) in osteoblasts using Cdh2flox/flox Osx-Cre mice. N-cadherin expression was efficient...
Differential contribution of osteoclast- and osteoblast-lineage cells to CpG-oligodeoxynucleotide (CpG-ODN) modulation of osteoclastogenesis. J. Bone Miner. Res. 2005, 20, 1692-1699.Amcheslavsky A, Hemmi H, Akira S, Bar-Shavit Z 2005 Dif- ferential contribution of osteoclast- and osteoblast-...
To test whether OPN+CD45−Ter119− cells were enriched for osteolineage cells, we isolated RNA from FACS-purified OPN+CD45−Ter119− cells and analyzed the expression of additional osteoblast-specific transcripts, including osteocalcin (OC), bone-specific alkaline phosphatase (ALP), osteoacti...