Opioid use disorder (OUD) has become an urgent health problem. People with OUD often experience comorbid medical conditions. Systematical approaches to identifying co-occurring conditions of OUD can facilitate a deeper understanding of OUD mechanisms and drug discovery. This study presents an integrated...
We searched for opioid poisoning and opioid use disorder from ICD-9 to ICD-10 code diagnosis after their initial injury. Patients that filled an opioid prescription within a 3-month period after sustaining the trauma were compared to those who did not, using Cox proportional hazards regressions....
opioid use disorderOUDprimary careruralBackground and Aims International Classification of Diseases (ICD) diagnosis codes are often used in research to identify patients with opioid use disorder (OUD), but their accuracy for this purpose is not fully evaluated. This study describes application of ICD...
In the past two decades, over-prescription of opioids for pain management has driven a steep increase in opioid use disorder (OUD) and death by overdose, exerting a dramatic toll on western countries. OUD is a chronic relapsing disease associated with a lifetime struggle to control drug consump...
use disorder. For example,GSG1Lhas been linked to plasma methadone levels48, and the myeloid zinc finger transcription factor MZF1 to cis-regulatory sequences driving expression of the mu-opioid receptor 149. Another noteworthy example of a PhenomeX substance use-linked candidate gene with altered...
Unadjusted Mean Number of Opioid Use Disorder (OUD) Visits per Patient With OUD in a 12-Month Period View LargeDownload The low, medium, and high telemedicine use groups were based on clinicians’ telemedicine use across all outpatient visits. The prepandemic period was March 14, 2019, to ...
Results shown only for patients who had not received treatment for opioid use disorder in the 90 days before the index opioid overdose. Race/ethnicity was self-reported or derived from other administrative data sources. Table 1. Characteristics of Patient Cohort, Stratified by Overdose Typea View ...
Substanceusedisorder Opioids11(8.2)4027(0.3)272.4(152.2-487.2)aThe95%CIswerecalculatedusing theWilsonScoremethod. Illicitdrugs13(9.7)7079(0.5)183.3(107.2-313.4) bOperationtypesarenotmutually Alcohol8(6.0)10131(0.8)78.9(40.0-155.6) exclusive.
Substance misuse is associated with poor asthma outcome and death. People with opioid use disorder (OUD) may be at particular risk, however, there have been no case-control studies of asthma care and outcomes in this patient group. A primary care databas
Illicit Drug Use LLM: Large Language Model LSTM: Long-Short-Term Memory MT: Multi-Task Neg: Negation NER: Named Entity Recognition NLP: Natural Language Processing OUD: Opioid Use Disorder RoBERTa: Robustly Optimized BERT Pre-training Approach Sev: Severity ShARe: Shared Annotated ...