In OP9-DL1 cocultures, EML cell line has differentiated into cells that 1) resembled double-negative, double-positive, and single-positive stages of T-cell development; 2) initiated expression of GATA-3, Pre-T伪, RAG-1, and T-cell receptor鈥揤尾 genes; and 3) produced interferon-纬 in...
OP9-DL1 is a murine stromal cell line that mimics thymic microenvironments to support T cell development in vitro and provides a useful tool to study T lymphocyte lineage commitment [14] and thymic adipogenesis [31, 38]. In order to identify key regulators in thymic adipogenesis, the present...
Bone Marrow CellsCell LineMacrophagesAnimalsMice, Inbred C3HMiceCongenitally athymic (nude) mice exhibited an anomalous high resistance against infections with ... PETER F. BONVENTRE - 《Infection & Immunity》 被引量: 72发表: 1978年 Adriamycin-induced activation of NK activity may initially involve ...